Supranormal FEV1, FVC values linked to better lung function

Nearly 3 percent of the general population demonstrate greater-than-expected values of forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), which are both indicative of a better lung function, according to a recent study in Austria.

A group of researchers examined the prevalence of supranormal FEV1 and FVC values in the LEAD* study, a general population cohort in Austria that included participants aged 6 to 82 years.

Among the general population, 3.4 percent had supranormal prebronchodilator FEV1 value and 3.1 percent had supranormal FVC value. These figures persisted across different age groups, except for participants aged >60 years, in whom the values increased (5.0 percent and 4.2 percent, respectively).

Nearly half of supranormal individuals had both increased FEV1 and FVC values. In addition, supranormal spirometric values were consistently associated with higher static lung volumes and lower specific airway resistance through the lifespan, which suggested better overall lung function.

In multivariate regression analysis, the following factors were found to have a consistent association with supranormal FEV1 and FVC values: female sex, higher muscle mass, less diabetes, and fewer respiratory symptoms.

“Supranormal FEV1 and/or FVC values occur in about 3 percent of the general population in different age bins and are associated with better health markers,” the researchers said.

*Lung, hEart, sociAl and boDy