News &amp; Updates

Waitlisted registrants for liver transplantation (LT) who have nonalcoholic steatohepatitis (NASH) cirrhosis have a lower chance to receive a new organ and greater risk of waitlist mortality at 90 days and 1 year than patients with non-NASH cirrhosis, suggest the results of a Singapore study.

Liver transplant candidates with NASH cirrhosis less likely to receive new organ

Aztreonam-avibactam cures serious infections due to Gram-negative bacteria

Treatment with aztreonam in combination with avibactam (ATM-AVI) results in favourable clinical response and is well tolerated in patients with complicated intra-abdominal infection (cIAI) and hospital-acquired or ventilator-associated pneumonia (HAP/VAP) due to Gram-negative bacteria, according to the results of the REVISIT study.

Aztreonam-avibactam cures serious infections due to Gram-negative bacteria

Dalbavancin an effective treatment option for serious gram-positive infections

In a real-world study presented at IDWeek 2023, dalbavancin has been shown to be an effective treatment alternative for patients with invasive gram-positive infections.

Dalbavancin an effective treatment option for serious gram-positive infections

Cardiac autonomic neuropathy a risk factor for silent myocardial infarction

Individuals with cardiac autonomic neuropathy appear to be at increased risk of incident silent myocardial infarction (SMI), regardless of the presence of traditional atherosclerotic risk factors, according to a study.

Cardiac autonomic neuropathy a risk factor for silent myocardial infarction

Small wins for amlitelimab in STREAM-AD

The experimental drug amlitelimab has scored positive outcomes in the double-blind, placebo-controlled phase IIb STREAM-AD study evaluating it as a treatment for moderate-to-severe atopic dermatitis (AD).

Small wins for amlitelimab in STREAM-AD

23 Oct 2023

Obeticholic acid shows therapeutic potential in LPAC syndrome

The selective farnesoid-X receptor agonist obeticholic acid appears to improve symptoms of low phospholipid-associated cholelithiasis (LPAC) syndrome in patients who have inadequate response or intolerance to ursodeoxycholic acid, as shown in a small study.

Obeticholic acid shows therapeutic potential in LPAC syndrome

Adult ADHD spells increased dementia risk

22 Oct 2023 by

Adults with attention-deficit/hyperactivity disorder (ADHD) face a nearly threefold higher risk of dementia compared with those who do not have the neurodevelopmental condition, according to a study.

Adult ADHD spells increased dementia risk

22 Oct 2023

Amino acid neurotransmitters predict death, disability after ischaemic stroke

Among patients who have had a stroke, those with increased glutamic acid, aspartic acid, and gamma-aminobutyric acid and decreased glycine in plasma are more susceptible to adverse outcomes, such as death or major disability, reveals a China study.

Amino acid neurotransmitters predict death, disability after ischaemic stroke

22 Oct 2023

Do alpha-1 receptor blockers help prevent COVID-19 hospitalization?

Frequent use of alpha-1 receptor blockers is neither harmful nor protective against the risk of uncomplicated or severe COVID-19 hospitalization, a study has shown.

Do alpha-1 receptor blockers help prevent COVID-19 hospitalization?

22 Oct 2023

Corpus callosotomy may reduce seizures in LGS after failure of vagus nerve stimulation

For children with Lennox-Gastaut syndrome (LGS) who have not achieved seizure control with vagus nerve stimulation, corpus callosotomy appears to help reduce all seizure subtypes, as shown in a study.

Corpus callosotomy may reduce seizures in LGS after failure of vagus nerve stimulation