News &amp; Updates

Internal fixation surgery did not significantly improve functional outcomes in patients with closed, displaced humeral shaft fractures compared with nonoperative functional bracing, the FISH* trial has shown.

Surgery no better than bracing for humeral fractures

Pembrolizumab not cost-effective for NSCLC in SG

Pembrolizumab monotherapy shows superior efficacy to standard chemotherapy for non-small cell lung cancer (NSCLC), according to a new Singapore study. However, its current pricing in the country makes it the less economical option.

Pembrolizumab not cost-effective for NSCLC in SG

LV diastolic dysfunction worsens LEAD outcomes

Left ventricular (LV) diastolic dysfunction increases the risk of major adverse cardiac and cerebrovascular events (MACCEs) in patients with lower extremity artery disease (LEAD), a recent study has shown.

LV diastolic dysfunction worsens LEAD outcomes

Shorter TB regimens to lower costs, improve disease control in high-burden areas

Use of appropriate antibiotics for just 4 months, 2 months, or even 7 days in the management of tuberculosis (TB) should be cost-effective and lead to better disease control, especially in settings with high incidence rates and poor treatment outcomes, as shown in a recent study from Taiwan.

Shorter TB regimens to lower costs, improve disease control in high-burden areas

Glucagon effective for hypoglycaemia in T1DM regardless of administration route

In conscious type 1 diabetes mellitus (T1DM) patients, administering glucagon intranasally is as effective at resolving hypoglycaemia as administering it via intramuscular/subcutaneous injections, according to the results of a meta-analysis.

Glucagon effective for hypoglycaemia in T1DM regardless of administration route

Web-based self-intervention may prevent depression in patients with persistent back pain

A guided web-based self-intervention, adapted from elements of cognitive behavioural therapy (CBT), may be effective in preventing the onset or recurrence of major depressive episodes (MDEs) in patients with persistent back pain, according to results of the recent PROD-BP study.

Web-based self-intervention may prevent depression in patients with persistent back pain

Omalizumab improves outcomes in chronic rhinosinusitis with nasal polyps

Treatment with omalizumab, an anti-IgE monoclonal antibody, significantly improves outcomes in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP), regardless of asthma status, based on a pooled analysis of the POLYP 1 and POLYP 2* studies presented at AAAAI 2020.

Omalizumab improves outcomes in chronic rhinosinusitis with nasal polyps

Relugolix combo therapy preserves bone mass in women with heavy period

02 Jun 2020 by

Combining the oral GnRH* receptor antagonist relugolix together with oestradiol and the progestin norethindrone helps protect against bone loss induced by oestrogen deprivation associated with the use of GnRH receptor antagonist monotherapy for treating heavy menstrual bleeding, according to the LIBERTY studies released during the ACOG 2020 Meeting.

Relugolix combo therapy preserves bone mass in women with heavy period

Distance travelled affects time to surgery in kids with focal cortical dysplasia

Sociodemographic factors appear to be important determinants of time to epilepsy surgery for children with focal cortical dysplasia, a new study has shown.

Distance travelled affects time to surgery in kids with focal cortical dysplasia

H. pylori treatment not tied to C. difficile infection

02 Jun 2020 by

Treatment of Helicobacter pylori (H. pylori) infection is not linked to an increased risk of Clostridium difficile (C. difficile) infection, according to a retrospective cohort study.

H. pylori treatment not tied to C. difficile infection