Clostridioides difficile Infection Disease Summary

Last updated: 11 November 2024

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Overview

Clostridioides (formerly Clostridium) difficile infection is commonly associated with antibiotic treatment and is one of the most common nosocomial infections.
Symptoms usually start on days 2-3 of antibiotic treatment, but may also occur up to 8-12 weeks after discontinuation of antibiotics.
Submitted stool specimens which are formed should not be used for laboratory testing.
The first step in otherwise healthy patients is to stop the offending antibiotic as soon as possible.

For further information regarding the management of Clostridioides difficile Infection, please refer to Disease Algorithm for the Treatment Guideline.