Diabetes Mellitus (Pediatric) Disease Summary

Last updated: 11 November 2024

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Overview

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.
Type 1 DM may present with hyperglycemia, glycosuria, and ketonuria with polyuria, polydipsia, polyphagia, and weight loss for several weeks; type 2 DM may present with obesity, glycosuria with ketonuria, absent or mild polyuria, ketoacidosis, and acanthosis nigricans.
DM can be diagnosed if polyuria, polydipsia, polyphagia, weight loss are present and FPG concentration is ≥126 mg/dL (7.0 mmol/L) and/or casual plasma glucose is ≥200 mg/dL (11.1 mmol/L).
Goals of therapy include maintaining a balance between tight glucose control and avoiding hypoglycemia, eliminating polyuria and nocturia, preventing ketoacidosis, and permitting normal growth and development.

For further information regarding the management of Diabetes Mellitus (Pediatric), please refer to Disease Algorithm for the Treatment Guideline.