Exercise helps keep depression at bay for children, teens

07 Jan 2023
Early life exercises improve bacteria health, says researchEarly life exercises improve bacteria health, says research

Physical activity interventions are beneficial to children’s mental health, with a recent study suggesting that working out helps reduce depressive symptoms in both children and adolescents.

Researchers conducted a systematic review and meta-analysis of studies that evaluated the effects of physical activity interventions on depressive symptoms in the paediatric population as compared with a control condition. They searched multiple online databases for relevant literature and used Hedges g to synthesize data. Meta-regressions and sensitivity analyses were also performed to substantiate the overall results.

A total of 21 studies, which comprised an overall population of 2,441 participants (mean age 14 years, 47.0 percent boys), were included in the meta-analysis. The primary endpoint was depressive symptoms, measured using validated depression scales after the intervention and at follow-up.

Pooled data showed that compared with the control condition, physical activity interventions were associated with a marked reduction in depressive symptoms (g, −0.29, 95 percent confidence interval [CI], −0.47 to −0.10; p=0.004).

Meanwhile, follow-up data from four studies showed no differences in the primary endpoint between the physical activity and control groups (g, −0.39, 95 percent CI, −1.01 to 0.24; p=0.14). There was moderate heterogeneity detected across the studies (Q, 53.92; p<0.001; I2, 62.9 percent).

Factors such as total physical activity volume, study design, participant health status, and allocation and/or assessment concealment did not moderate the main treatment effect. However, secondary analyses indicated that intervention (ie, <12 weeks in duration, 3 times per week, unsupervised) and participant characteristics (ie, aged ≥13 years, with a mental illness and/or depression diagnosis) might factor in the overall treatment effect.

More investigation is needed to elucidate the association with physical activity parameters such as frequency, duration, and supervision of the sessions.

JAMA Pediatr  2023;doi:10.1001/jamapediatrics.2022.5090