Turning the TIDES with Dengue Vaccination

Aedes aegypti mosquito is the epitome of ‘small bite, big threat’. A bite from a female Aedes aegypti mosquito is enough to spread dengue. There are four different serotypes of dengue virus, Dengue Virus 1–4 (DENV1–4), thus, individuals can be infected with dengue up to four times. Repeated infections increase the risk of severe dengue, a risk factor for mortality. These serotypes are endemic to a certain countries and cocirculate in the natural environment. Dengue poses a major global health concern, with approximately 40% of the world’s population at risk of infection and more severe cases linked to a 20% mortality rate.