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Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
Researchers from the University of Hong Kong (HKU) have developed a dry powder formulation of tamibaroterone, which displays broad-spectrum antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Middle East respiratory syndrome coronavirus (MERS-CoV), and pandemic 2009 influenza A virus (H1N1), when delivered intranasally or through inhalation in mouse and hamster models.
Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
12 Oct 2021Early convalescent plasma infusion does not prevent COVID-19 progression
An infusion of convalescent plasma, obtained via blood donation from individuals who have recovered from COVID-19, did not prevent disease progression in high-risk outpatients who presented within 7 days of COVID-19 symptom onset, results of the phase III US-based SIREN-C3PO* study showed.
Early convalescent plasma infusion does not prevent COVID-19 progression
11 Oct 2021Continuous vital sign monitoring catches COVID-19 deterioration early
A wearable chest patch device can continuously monitor vital signs in patients with the coronavirus disease 2019 (COVID-19), facilitating the early detection of cardiovascular deterioration, according to a recent study.
Continuous vital sign monitoring catches COVID-19 deterioration early
11 Oct 2021Early intubation tied to better survival in COVID-19 patients with ARDS
Late intubation compounds the risk of death among coronavirus disease 2019 (COVID-19) patients on mechanical intubation due to respiratory insufficiency, a recent study has found.
Early intubation tied to better survival in COVID-19 patients with ARDS
11 Oct 2021Antiviral monoclonal antibody therapies may prevent hospitalization in nonsevere COVID-19
The antiviral monoclonal antibodies casirivimab-imdevimab appear to reduce the risk of hospitalization in patients with nonsevere COVID-19, as do bamlanivimab, bamlanivimab-etesevimab, and sotrovimab, according to the results of a systematic review and meta-analysis.
Antiviral monoclonal antibody therapies may prevent hospitalization in nonsevere COVID-19
08 Oct 2021SG Shield confers protection during COVID-19 swab tests
A manikin study has shown that use of the standard face shield is not enough to protect against droplet dispersion during oropharyngeal COVID-19 swabs, but the SG Shield results in significant reduction of droplet contamination to the swab provider’s face and chest.
SG Shield confers protection during COVID-19 swab tests
06 Oct 2021Cardiac manifestations after COVID-19 jabs: When do they arise and who are at risk?
Cardiac manifestations, such as acute myocardial infarction (AMI) and myocarditis, after vaccination for the coronavirus disease 2019 (COVID-19) are more common in men, according to a recent Singapore study. AMI is more likely to arise after the first shot, while myocarditis becomes more common after the second dose.