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![[HKU Medical Grand Rounds] Angels and demons: Immunotherapy for treatment of advanced hepatocellular carcinoma](https://sitmspst.blob.core.windows.net/images/articles/angels-and-demons-3cde1853-f09a-4511-a0c7-1794e52dc9d8-square.jpg)
ALK+ NSCLC: Real-world patterns and outcomes of treatment after 1L brigatinib
Following first-line (1L) brigatinib treatment, most patients with ALK-positive (ALK+) non-small-cell lung cancer (NSCLC) received an ALK tyrosine kinase inhibitor (TKI) as second-line (2L) therapy and experienced prolonged clinical benefit, a retrospective chart review of patients enrolled in the phase III ALTA-1L trial has shown.
ALK+ NSCLC: Real-world patterns and outcomes of treatment after 1L brigatinib
17 Jul 2024![[test headline bait]Amivantamab plus chemo tied to better outcomes in NSCLC](https://sitmspst.blob.core.windows.net/images/articles/amivantamab-plus-chemo-tied-to-better-outcomes-vs-chemo-alone-in-advanced-nsclc-4c5757ec-0008-423f-84f1-77e75dacf343-square.jpg)
[test headline bait]Amivantamab plus chemo tied to better outcomes in NSCLC
Treatment with amivantamab (ami) in combination with chemotherapy (chemo) results in substantially longer time to treatment discontinuation (TTD), time to subsequent therapy (TTST), and progression-free survival (PFS) after first subsequent therapy (PFS2) in patients with EGFR-mutant advanced nonsmall cell lung cancer (NSCLC) following progression on osimertinib, as shown in a postprogression analysis.
[test headline bait]Amivantamab plus chemo tied to better outcomes in NSCLC
17 Jul 2024
Lung cancer screening tied to reduced mortality
In an observational study conducted in Poland, individuals who participated in a low-dose computed tomography (LDCT) lung cancer screening programme had a reduction in all-cause mortality compared with a matched control group extracted from a general Polish cohort.
Lung cancer screening tied to reduced mortality
02 Jul 2024
Neoadjuvant cycles do not alter perioperative nivolumab benefit in resectable NSCLC
Treatment with nivolumab plus chemotherapy before surgery followed by nivolumab after surgery yields superior outcomes for patients with resectable nonsmall cell lung cancer (NSCLC) as compared with placebo plus chemotherapy, regardless of the number of completed neoadjuvant cycles, according to an exploratory analysis of the CHECKMATE 77T trial.
Neoadjuvant cycles do not alter perioperative nivolumab benefit in resectable NSCLC
02 Jul 2024
Subcutaneous atezolizumab favoured over intravenous infusion
Nonsmall cell lung cancer (NSCLC) patients with high PD-L1 expression appear to show a strong preference for receiving atezolizumab subcutaneously rather than intravenously.
Subcutaneous atezolizumab favoured over intravenous infusion
02 Jul 2024
Legume intake reduces colorectal cancer risk
Eating legumes may help avert the development of colorectal cancer, according to a study that has found an inverse association between legume consumption and colorectal cancer risk.
