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Tumour immune barrier determines immunotherapy efficacy in HCC
A tumour immune barrier (TIB) structure formed by the interaction of SPP1+ macrophages and cancer-associated fibroblasts (CAFs) appears to influence the efficacy of immunotherapy in patients with hepatocellular carcinoma (HCC), reveals a study.
Tumour immune barrier determines immunotherapy efficacy in HCC
01 Apr 2023
Secukinumab yields sustained positive effects on molecular, histopathologic psoriasis markers
Treatment with secukinumab leads to sustained clinical response among patients with psoriasis, with clinical response being associated with rapid and persistent normalization of keratin 16 (K16) and inflammatory gene expression for most patients, according to data from the ObePso-S study.
Secukinumab yields sustained positive effects on molecular, histopathologic psoriasis markers
01 Apr 2023
Systemic antihypertensive medications exert diverse effects on glaucoma, IOP
The effects of systemic antihypertensive medications on glaucoma and intraocular pressure (IOP) appear to vary widely, according to the results of a systematic review and meta-analysis.
Systemic antihypertensive medications exert diverse effects on glaucoma, IOP
31 Mar 2023
Certain ART combinations carry some risk of depression among women with HIV
Women with HIV who use antiretroviral therapy (ART) combinations such as tenofovir alafenamide (TAF) with a cobicistat-boosted integrase inhibitor (INSTI) or protease inhibitor (PI) appear to frequently show somatic depressive symptoms, according to data from the Women’s Interagency HIV Study (WIHS) presented at CROI 2023.
Certain ART combinations carry some risk of depression among women with HIV
31 Mar 2023
Oral HBV cccDNA inhibitor a promising cure against chronic HBV infection
A recent study has found a small-molecule covalently closed circular DNA (cccDNA) inhibitor that reduces levels of hepatitis B virus (HBV) cccDNA. This discovery offers a new way to cure patients with chronic HBV infection.
