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Clinical insights on best medical therapy for peripheral artery disease
Patients with lower extremity peripheral artery disease (PAD) are at high risk for major adverse cardiovascular events (MACE), major adverse limb events (MALE), mortality, and future major lower extremity amputation (LEA). PAD patients with multivessel disease or relevant comorbidities such as diabetes and kidney failure are at an even higher risks for such events. [Lancet 2018;391:219-229]
Clinical insights on best medical therapy for peripheral artery disease
02 Dec 2021Cardiorenal benefit with investigational GLP-1 RA independent of concurrent SGLT2 inhibitor
The glucagon-like peptide-1 receptor agonist (GLP-1 RA) efpeglenatide affords cardiovascular and renal protection that is not explained by concurrent use of a sodium-glucose co-transporter-2 (SGLT2) inhibitor in patients with type 2 diabetes (T2D), according to an exploratory analysis of AMPLITUDE-O.
Cardiorenal benefit with investigational GLP-1 RA independent of concurrent SGLT2 inhibitor
30 Nov 2021Remnant cholesterol tied to CVD death in patients with T2D, CKD, diabetic nephropathy
Remnant cholesterol (C) appears predictive of mortality due to cardiovascular disease (CVD) among patients with type 2 diabetes (T2D), chronic kidney disease (CKD) stage 3 to 5, and incident diabetic nephropathy (DN), suggests a study.
Remnant cholesterol tied to CVD death in patients with T2D, CKD, diabetic nephropathy
29 Nov 2021Add-on ezetimibe helps reduce LDL-C in post-ACS patients
The addition of ezetimibe to a statin led to reductions in low-density lipoprotein-cholesterol (LDL-C) in patients who have been stabilized after the presentation of an acute coronary syndrome (ACS), according to data presented at AHA 2021.
Add-on ezetimibe helps reduce LDL-C in post-ACS patients
29 Nov 2021No causal link between COVID-19 and atrial fibrillation
Patients with the coronavirus disease 2019 (COVID-19), even those genetically predisposed to the disease, are not at increased risk of developing atrial fibrillation, and vice versa, a study has found.