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Does early antihypertensive treatment prevent death in stroke patients?
Early antihypertensive treatment appears to have no significant benefits in terms of dependency or death at 90 days among patients with mild-to-moderate acute ischaemic stroke and systolic blood pressure (SBP) between 140 and <220 mm Hg, reports a study.
Does early antihypertensive treatment prevent death in stroke patients?
17 Oct 2023ARCADIA trials: A win for nemolizumab in atopic dermatitis
In the phase III ARCADIA 1 and 2 trials, the investigational, first-in-class interleukin-31-Rα antagonist nemolizumab delivered early, rapid, and sustained improvements in the core signs and symptoms of atopic dermatitis (AD) in patients with moderate-to-severe disease.
ARCADIA trials: A win for nemolizumab in atopic dermatitis
17 Oct 2023Prednisolone ≥5 mg/day doubles risk of MACE in RA patients
In patients with rheumatoid arthritis (RA), use of systemic glucocorticoids (GC) is associated with a time- and dose-dependent increase in risk of major adverse cardiovascular events (MACE), a population-based real-world study has shown. On long-term follow-up, a prednisolone dose of ≥5 mg/day is associated with a doubled risk of MACE vs no GC use, and no safe duration of use is found for this daily GC dose.
Prednisolone ≥5 mg/day doubles risk of MACE in RA patients
17 Oct 2023Dapagliflozin cuts HbA1c in paediatric T2D
Dapagliflozin reduced HbA1c by 1.03 percentage points more than placebo in children and adolescents with type 2 diabetes (T2D), while saxagliptin showed no significant reduction vs placebo in the phase III T2NOW trial presented at EASD 2023.
Dapagliflozin cuts HbA1c in paediatric T2D
17 Oct 2023First-line therapies for advanced NSCLC improve survival, QoL
Clinical trials on first-line therapies for advanced or metastatic nonsmall cell lung cancer (NSCLC) from 2010 to 2020 have reported better survival and a steady improvement in quality of life (QoL) among patients, according to the results of a systematic review.
First-line therapies for advanced NSCLC improve survival, QoL
16 Oct 2023Behavioural interventions improve screening colonoscopy uptake
Use of behavioural interventions, specifically multicomponent and patient navigation interventions, helps increase the uptake of colonoscopy for colorectal cancer (CRC) screening, reveals a study.
Behavioural interventions improve screening colonoscopy uptake
16 Oct 2023Social deprivation tied to higher glaucoma risk
Personal poverty, as defined by not driving a personal vehicle to the appointment, and neighbourhood-level poverty appear to contribute to higher rates of screening positive for glaucoma or suspected glaucoma, suggests a study.