News & Updates

Among pregnant individuals on antiretroviral therapy (ART) for HIV-1 infection, those on dolutegravir had the greatest viral suppression rates at delivery, a recent US-based observational study showed. However, birth outcomes generally did not differ between dolutegravir recipients and those on various other ART regimens.

Initiating a once-weekly treatment regimen of semaglutide helps control glycated haemoglobin (HbA1c) levels and body weight in patients with type 2 diabetes, without introducing new safety concerns, a Japan study has found.

Older adults with well-controlled metabolic comorbidities exhibit immune response to influenza vaccine, as shown in the results of the DYNAMIC study. Notably, physical activity further increases immune response particularly for influenza A/H3N2.

In thrombotic stroke patients at high risk of ischaemic stroke recurrence, prasugrel was as effective as clopidogrel in reducing the composite incidence of ischaemic stroke, MI, and death from other vascular causes, the phase III PRASTRO-III study has shown.

A recent study recommends the use of pembrolizumab over BRAF/mitogen-activated protein kinase inhibitors, such as dabrafenib/trametinib, as first-line treatment in patients with advanced BRAF V600‒mutant advanced malignant melanoma.

The presence of atrial fibrillation (AF) at baseline does not appear to modify the benefits of dapagliflozin, compared with placebo, on symptoms and clinical events in patients with heart failure and preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF), according to a study.