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Osimertinib plus chemo bumps up PFS in advanced EGFR-mutated NSCLC
In the first-line treatment of patients with advanced nonsmall cell lung cancer (NSCLC) harbouring EGFR mutation, the combination of osimertinib plus pemetrexed and platinum-based chemotherapy outperformed osimertinib alone in terms of extending progression-free survival (PFS), according to the interim results of the phase III FLAURA2 trial presented at WCLC 2023.
Osimertinib plus chemo bumps up PFS in advanced EGFR-mutated NSCLC
12 Oct 2023
ICI-related adverse events tied to longer survival in metastatic NSCLC
Immune-related adverse events (irAEs) are more likely to develop in metastatic nonsmall cell lung cancer (NSCLC) patients with certain prognostic characteristics, suggests a study. Interestingly, those who develop irAEs benefit from a much longer overall survival (OS) and time to next treatment when mitigating immortal time bias.
ICI-related adverse events tied to longer survival in metastatic NSCLC
08 Oct 2023
Canakinumab improves survival in advanced NSCLC
Treatment with canakinumab appears beneficial to patients with advanced nonsmall cell lung cancer (NSCLC) with low T-cell infiltration (ie, low total count or immune desert phenotype), results of predefined exploratory biomarker analyses from the CANOPY-1 have shown.
Canakinumab improves survival in advanced NSCLC
07 Oct 2023
COVID vs non-COVID ARDS: Are both mentally distressing for patients’ kin?
Mental health symptoms of family members of patients hospitalized for acute respiratory distress syndrome (ARDS) were similar at 12 months regardless of whether it was caused by COVID-19 or not, a prospective cohort study suggests.
COVID vs non-COVID ARDS: Are both mentally distressing for patients’ kin?
04 Oct 2023
Serplulimab-chemo shows promise for squamous NSCLC
Patients with previously untreated, locally advanced, or metastatic squamous non-small-cell lung cancer (NSCLC) may derive benefit from the addition of the novel anti-PD-1 monoclonal antibody serplulimab to chemotherapy, according to the final analysis of the phase III ASTRUM-004 study.
Serplulimab-chemo shows promise for squamous NSCLC
03 Oct 2023
Low visceral fat area predicts poor survival in cancer patients
Visceral fat area (VFA) is a reliable prognostic indicator of muscle mass and is associated with nutritional, immune, and inflammatory status in patients with diverse types of cancer, such as gastric, colorectal, and nonsmall-cell lung cancers (NSCLC), claims a recent study.