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Diabetes, obesity tied to upstaging in renal cell carcinoma
Diabetes and higher body mass index (BMI) contribute to pathological upstaging in renal cell carcinoma, according to a study. Preoperative tumour size, increased age, and male sex are also significantly associated with upstaging.
Diabetes, obesity tied to upstaging in renal cell carcinoma
07 Nov 2023Adding pembrolizumab to cCRT ups PFS in high-risk locally advanced cervical cancer
In patients with newly diagnosed, previously untreated, high-risk locally advanced cervical cancer, adding pembrolizumab to concurrent chemoradiotherapy (cCRT) significantly improves progression-free survival (PFS) vs cCRT alone, according to results of the phase III ENGOT-cx11/GOG-3047/KEYNOTE-A18 study presented at European Society for Medical Oncology Congress 2023 (ESMO 2023).
Adding pembrolizumab to cCRT ups PFS in high-risk locally advanced cervical cancer
06 Nov 2023Add-on immunotherapy prolongs survival in advanced endometrial cancer
In the treatment of patients with advanced or recurrent endometrial carcinoma, adding the PD-L1 inhibitor atezolizumab to chemotherapy helps lower the risk of progression or death, according to the phase III AtTEnd trial.
Add-on immunotherapy prolongs survival in advanced endometrial cancer
03 Nov 2023Enfortumab vedotin-pembrolizumab beats chemo as 1L Tx for bladder cancer
In the phase III EV-302/KEYNOTE-A39 trial, the combination of enfortumab vedotin and pembrolizumab (EV+P) had a significant survival advantage over chemotherapy in the first-line treatment of patients with locally advanced metastatic urothelial carcinoma (la/mUC).
Enfortumab vedotin-pembrolizumab beats chemo as 1L Tx for bladder cancer
03 Nov 2023Biomarker-driven therapies superior to standard care in breast cancer
Patients with breast cancer may gain greater therapeutic advantages from biomarker-driven than standard-of-care therapies, suggests a study.
Biomarker-driven therapies superior to standard care in breast cancer
02 Nov 2023Histologic margin status predicts relapse in lentigo maligna melanoma
Histologic margin status shows a robust association with progression for lentigo maligna melanoma, suggest the results of a recent study.