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Second bDMARD after failure of non-TNFi biologic in RA shows modest drug survival, response
A recent study has shown modest drug survival and primary response of a second biologic disease-modifying antirheumatic drug (bDMARD) in patients with rheumatoid arthritis (RA) switching due to failure of a nontumour necrosis factor inhibitor (non-TNFi) bDMARD as the first agent.
Second bDMARD after failure of non-TNFi biologic in RA shows modest drug survival, response
14 Oct 2021Smoking reduces effect of methotrexate-based treatment in RA patients
Current smoking reduces the response of patients with early rheumatoid arthritis (RA) to methotrexate (MTX) in a dose-responsive manner, regardless of concomitant prednisone use, a recent study has found.
Smoking reduces effect of methotrexate-based treatment in RA patients
14 Oct 2021Lenzilumab reduces likelihood of survival without ventilation in COVID-19 patients
In hospitalized COVID-19 patients, treatment with the novel GM-CSF* neutralizing monoclonal antibody lenzilumab led to a significant improvement in survival without invasive mechanical ventilation (SWOV), findings from the phase III LIVE-AIR study suggest.
Lenzilumab reduces likelihood of survival without ventilation in COVID-19 patients
14 Oct 2021Common, cheap osteoporosis drug promising for T2D
The osteoporosis drug alendronate halves the risk of developing type 2 diabetes (T2D) in a nationwide, retrospective, case-control study of nearly 700,000 patients from Denmark.
Common, cheap osteoporosis drug promising for T2D
14 Oct 2021Dapagliflozin improves symptoms, physical limitations in HFpEF
Patients with heart failure and preserved ejection fraction (HFpEF) treated with dapagliflozin experienced improvements in symptoms and physical limitations, according to results of the PRESERVED-HF study presented at HFSA 2021.
Dapagliflozin improves symptoms, physical limitations in HFpEF
13 Oct 2021Cilostazol makes good in DAPT for recurrent stroke prevention in high-risk patients
Dual antiplatelet therapy (DAPT) with cilostazol performs better than either aspirin or clopidogrel alone at reducing the risk of recurrent stroke or vascular events without increasing the incidence of bleeding for patients with ischaemic stroke and intracranial arterial stenosis, according to the results of the CSPS.com* trial.