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Higher vitamin D dose beneficial for paediatric obesity-related asthma
A 50,000-IU loading dose of oral vitamin D plus 8,000 IU daily is effective and safe for increasing serum 25(OH)D levels to ≥40 ng/mL in children and adolescents with asthma who were overweight or obese, as opposed to the standard of care (SoC) dose of 600 IU daily, according to findings from the VDORA1* trial.
Higher vitamin D dose beneficial for paediatric obesity-related asthma
23 May 2023Dupilumab cuts exacerbations, improves lung function in paediatric asthma patients with high eosinophils
In the post hoc analysis of data from the phase III LIBERTY ASTHMA VOYAGE study, the monoclonal antibody dupilumab reduced exacerbations and improved lung function in children aged between 6 and 11 years with moderate-to-severe asthma and baseline blood eosinophil count of ≥500 cells/μL.
Dupilumab cuts exacerbations, improves lung function in paediatric asthma patients with high eosinophils
22 May 2023Algorithm useful in evaluating COVID-19 reinfection cases in Singapore
A study from Singapore demonstrated the usefulness of a systematic programme using combined microbiologic, serologic, and genomic criteria to assess possible COVID-19 reinfection cases.