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Abrocitinib effectively manages AD flares
Rescue therapy using the Janus kinase 1 inhibitor abrocitinib combined with topical medicated therapy recaptured efficacy responses and had a favourable safety profile in individuals with moderate-to-severe atopic dermatitis (AD) who experienced flare during the maintenance period of the phase III randomized-withdrawal JADE REGIMEN trial.
Abrocitinib effectively manages AD flares
21 Mar 2022
Antihypertensive drugs up risk of psoriasis
Use of antihypertensive medications is associated with the incidence of psoriasis, reports a study. Beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers (CCBs), and thiazide diuretics result in an increased risk of psoriasis.
Antihypertensive drugs up risk of psoriasis
17 Mar 2022
Adalimumab–methotrexate combo better than adalimumab monotherapy in psoriasis
In the treatment of patients with psoriasis, the combination of adalimumab plus methotrexate is more beneficial than adalimumab alone, reducing antidrug antibody formation and inducing slightly better response, drug survival, and higher serum trough concentrations, according to a study.
Adalimumab–methotrexate combo better than adalimumab monotherapy in psoriasis
14 Mar 2022
Upadacitinib shows promise for long-term AD treatment
Upadacitinib with topical corticosteroids shows good long-term efficacy and safety in patients with moderate-to-severe atopic dermatitis (AD), reports a recent follow-up analysis to the AD Up study.
Upadacitinib shows promise for long-term AD treatment
12 Mar 2022
Adherence higher, discontinuation lower with ixekizumab vs secukinumab
Psoriasis patients treated with ixekizumab show better persistence and adherence over 24 months as well as a lower risk of discontinuation than those using secukinumab, reports a recent study that used real-world data.
Adherence higher, discontinuation lower with ixekizumab vs secukinumab
07 Mar 2022
Ustekinumab safe, effective in Asians with severe plaque psoriasis
Ustekinumab, a human monoclonal antibody that binds to the p40 subunit of both interleukin (IL)-12 and IL-23, demonstrates effectiveness and safety in the treatment of multiethnic Asian patients with moderate to severe plaque psoriasis, according to a Singapore study.
Ustekinumab safe, effective in Asians with severe plaque psoriasis
04 Mar 2022
Ligelizumab improves symptoms, QoL in patients with urticaria
In patients with chronic spontaneous urticaria (CSU) who remained symptomatic despite treatment, the monoclonal anti-immunoglobulin E antibody ligelizumab improved symptom control regardless of BHRA* status, as well as dermatology quality of life (QoL) regardless of angioedema status, findings from a phase IIb study have shown.