News &amp; Updates

Use of apremilast does not provide any clinical benefit in patients with active ankylosing spondylitis (AS), but the safety and tolerability of this treatment are consistent with its known profile, reports a study.

Apremilast fails to deliver clinical benefits in active ankylosing spondylitis

Risk of adverse pregnancy complications similar between insulin detemir, other basal insulins

Among women with pre-existing diabetes, the risks of major congenital malformations and other severe adverse pregnancy complications associated with insulin detemir do not differ from those of other basal insulins, according to a study.

Risk of adverse pregnancy complications similar between insulin detemir, other basal insulins

Current PPI use not a factor in COVID-19 outcomes

Proton pump inhibitors (PPIs) have been linked to higher risk of SARS-CoV-2 infection and hospital admission, but a recent study suggests that this is not the case. Specifically, the risk of hospital admission seen for current PPI users may be explained by residual confounding, and there is no association between PPI use and severity of COVID-19 among hospitalized patients.

Current PPI use not a factor in COVID-19 outcomes

Secukinumab improves enthesitis in patients with ankylosing spondylitis

In patients with ankylosing spondylitis (AS), treatment with secukinumab leads to improvement in enthesitis at overall Maastricht AS Enthesitis Score (MASES) and axial sites, results of a recent study have shown.

Secukinumab improves enthesitis in patients with ankylosing spondylitis

What is the most effective DAPT strategy for acute coronary syndrome treatment?

De-escalation of dual antiplatelet therapy (DAPT) is the most effective approach for the treatment of acute coronary syndrome (ACS), which leads to fewer bleeding events without increasing ischaemic events, compared with other established uses of DAPT, reveals a recent study.

What is the most effective DAPT strategy for acute coronary syndrome treatment?

Adjunctive sucralfate falls short of improving oral intake in kids with infectious mouth ulcers

Use of sucralfate as an adjunct to analgesics does not appear to help improve oral intake of children with acute oral infectious ulcers, as shown in a study.

Adjunctive sucralfate falls short of improving oral intake in kids with infectious mouth ulcers

Abrocitinib induction, maintenance effective against atopic dermatitis

Induction with abrocitinib is effective against atopic dermatitis, and continuous treatment helps suppress flares, a new trial has shown. Similarly, rescue treatment with abrocitinib in combination with topical therapy is able to recapture response.

Abrocitinib induction, maintenance effective against atopic dermatitis

Low-intensity statin plus ezetimibe lowers LDL better than moderate-intensity statin alone

26 Aug 2021 by

The combination of low-dose rosuvastatin plus ezetimibe represents a favourable alternative to moderate-intensity rosuvastatin alone for cholesterol management, with the combination more effective at lowering low-density lipoprotein cholesterol (LDL-C) and achieving LDL-C goals, as shown in a study.

Low-intensity statin plus ezetimibe lowers LDL better than moderate-intensity statin alone

HRT, progesterone use protective against high-risk serrated polyps

Women who are exposed to hormone replacement therapy (HRT) or medications that contain progesterone regardless of duration are less likely to develop high-risk serrated polyps (HRSP), according to a study.

HRT, progesterone use protective against high-risk serrated polyps