News & Updates

The Emerging Role of Biosimilars in Value-Based Medicine

01 Dec 2022

Biologic medicines and biosimilars
Biologic medicines are a category of very specific, highly effective medicines produced by a sophisticated and complex process involving living system¹. Most of them are very large, complex molecules or mixtures of molecules, and many are produced using recombinant DNA technology. These medicines have revolutionised the treatment and prevention of many disabling and life-threatening diseases including cancers, Crohn’s disease, ulcerative colitis, diabetes, rheumatoid arthritis, osteoporosis, psoriasis, human immunodeficiency virus, multiple sclerosis, growth deficiencies, and more¹.

The Emerging Role of Biosimilars in Value-Based Medicine

01 Dec 2022

Age, sex, syphilis risk factors for COVID-19 in PLHIV

30 Nov 2022 by

Among people living with HIV (PLHIV), young women and patients with active syphilis appeared to be at an elevated risk of contracting COVID-19, according to a cross-sectional study presented at HIV Glasgow 2022.

Age, sex, syphilis risk factors for COVID-19 in PLHIV

30 Nov 2022

Intensive antihypertensive therapy vital in kids with arterial hypertension after CoA repair

30 Nov 2022

Close blood pressure (BP) monitoring and more intensive and combined antihypertensive therapy are needed when there is a high prevalence of uncontrolled arterial hypertension (AH) despite the successful coarctation of the aorta (CoA) correction and use of relatively low doses of antihypertensive drugs, suggests a recent study.

Intensive antihypertensive therapy vital in kids with arterial hypertension after CoA repair

30 Nov 2022

Ascending aortic diameter predicts aortic dissection better than size index in Turner syndrome

30 Nov 2022

Among women with Turner syndrome (TS), aortic dissection appears to be more correlated with the ascending aortic diameter (AAD) than with aortic size index (ASI), a new study has found. TS-specific z-score is also a reliable predictor of dissection.

Ascending aortic diameter predicts aortic dissection better than size index in Turner syndrome

30 Nov 2022

Pituitary TF–based classification improves diagnostic accuracy and prognostication of nonfunctioning PitNETs

30 Nov 2022 by

Utility of pituitary transcription factors (TFs) improves the diagnostic accuracy and prognostication of nonfunctioning pituitary neuroendocrine tumours (NF-PitNETs), according to local data and a new diagnostic classification presented at the 5^th Annual Meeting of Endocrinology, Diabetes & Metabolism Hong Kong (EDM HK).

Pituitary TF–based classification improves diagnostic accuracy and prognostication of nonfunctioning PitNETs

30 Nov 2022

FRESCO-2: Fruquintinib improves OS in heavily pretreated mCRC

30 Nov 2022 by

Fruquintinib, a highly selective and potent oral tyrosine kinase inhibitor of VEGFR*-1, -2, and -3, significantly improves overall survival (OS) in heavily pretreated patients with metastatic colorectal cancer (mCRC), according to the FRESCO-2** trial presented at ESMO 2022.

FRESCO-2: Fruquintinib improves OS in heavily pretreated mCRC

30 Nov 2022

MEFIB bests MAST, FAST for fibrosis detection in NAFLD

29 Nov 2022

Magnetic resonance elastography (MRE) plus FIB-4 (MEFIB) outperforms both magnetic resonance imaging [MRI]-aspartate aminotransferase (MAST) and FibroScan-AST (FAST) in detecting stage ≥2 fibrosis and at-risk nonalcoholic steatohepatitis (NASH), reveals a study.

MEFIB bests MAST, FAST for fibrosis detection in NAFLD

29 Nov 2022

Do aortic annular size, valve type affect outcomes after TAVI?

29 Nov 2022 by

Aortic annular size does not appear to have a major impact on valve haemodynamics, prosthesis-patient match (PPM), and mortality following transcatheter aortic valve implantation (TAVI), according to the results of a Singapore study.