News & Updates

Add-on injectable agent may alter hypertension treatment landscape

11 Apr 2024 by

Patients with inadequately controlled hypertension (HTN) may benefit from a single subcutaneous (SC) injection of the investigational RNAi therapeutic zilebesiran, on top of standard antihypertensives, findings from the phase II KARDIA-2 trial suggest.

Add-on injectable agent may alter hypertension treatment landscape

11 Apr 2024

Transient elastography scores accurately predict liver-related events in MASLD

11 Apr 2024 by

Vibration-controlled transient elastography (VCTE)–based Agile scores, developed for diagnosis of advanced fibrosis (Agile 3+ score) and cirrhosis (Agile 4 score) in patients with metabolic dysfunction–associated steatotic liver disease (MASLD), are highly accurate in predicting liver-related events (LREs) and may be suitable alternatives to liver biopsy in routine clinical practice and phase IIb/III clinical trials for steatohepatitis, researchers from the VCTE-Prognosis Study Group have reported.

Transient elastography scores accurately predict liver-related events in MASLD

11 Apr 2024

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

11 Apr 2024 by

Excessive daytime sleepiness (EDS) is a risk factor for behavioural and emotional issues in children with obstructive sleep apnoea (OSA), researchers from the Chinese University of Hong Kong (CUHK) have shown.

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

11 Apr 2024

Product Highlight - LYPSTAPLUS

11 Apr 2024

Rosuvastatin + Ezetimibe 10/10 mg and 20/10 mg film-coated tablet

Product Highlight - LYPSTAPLUS

11 Apr 2024

Does the ACC pathway work for patients with chest pain?

10 Apr 2024

The expert consensus decision pathway recently published by the American College of Cardiology (ACC) has demonstrated its safety and efficacy in people with chest pain participating in an observational cohort study. However, those with coronary artery disease (CAD) may not benefit from such strategy.

Does the ACC pathway work for patients with chest pain?

10 Apr 2024

TriClip device gets FDA nod for leaky heart valve

10 Apr 2024 by

The US Food and Drug Administration (FDA) has approved the TriClip device for transcatheter edge-to-edge repair (TEER) in patients with severe tricuspid regurgitation (TR) or a leaky heart valve who are not eligible for surgery.

TriClip device gets FDA nod for leaky heart valve

10 Apr 2024

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

10 Apr 2024 by

Treatment with plozasiran, an experimental small interfering–RNA drug that targets apolipoprotein C3 (APOC3) gene, helps regulate triglyceride levels, bringing them below the critical threshold associated with acute pancreatitis for most patients with severe hypertriglyceridemia, according to the phase IIb SHASTA-2* study.

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

10 Apr 2024

Aprocitentan gets FDA nod for uncontrolled HTN

10 Apr 2024 by

The US Food and Drug Administration (FDA) has approved aprocitentan for the treatment of uncontrolled hypertension (HTN) in adults.

Aprocitentan gets FDA nod for uncontrolled HTN

10 Apr 2024

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

10 Apr 2024

Gartisertib, an oral inhibitor of ataxia telangiectasia and Rad3-related protein (ATR), for patients with advanced solid tumours is well tolerated at lower doses, according to the results of a phase I study. However, unexpected liver toxicity prevents dose escalation and, in turn, limits the drug’s antitumour activity.

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

10 Apr 2024

Healthy diet fails to offset diabetes risk for short sleepers

09 Apr 2024

A recent study suggests that adopting a healthy diet does protect against the risk of developing type 2 diabetes (T2D) among people with habitual short sleep duration, according to a study.

Healthy diet fails to offset diabetes risk for short sleepers

09 Apr 2024

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Add-on injectable agent may alter hypertension treatment landscape

Add-on injectable agent may alter hypertension treatment landscape

Transient elastography scores accurately predict liver-related events in MASLD

Transient elastography scores accurately predict liver-related events in MASLD

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

Daytime sleepiness: A hidden cause of behavioural and emotional issues in OSA children

Product Highlight - LYPSTAPLUS

Product Highlight - LYPSTAPLUS

Does the ACC pathway work for patients with chest pain?

Does the ACC pathway work for patients with chest pain?

TriClip device gets FDA nod for leaky heart valve

TriClip device gets FDA nod for leaky heart valve

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

APOC3 inhibition shows therapeutic potential in severe hypertriglyceridemia

Aprocitentan gets FDA nod for uncontrolled HTN

Aprocitentan gets FDA nod for uncontrolled HTN

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

Healthy diet fails to offset diabetes risk for short sleepers

Healthy diet fails to offset diabetes risk for short sleepers