News &amp; Updates

When administered concomitantly with oxytocin, prophylactic granisetron appears to have no negative impact on myometrial contraction during caesarean delivery, reports a recent study.

Granisetron prophylaxis does not affect myometrial contraction during caesarean birth

Second-line NIVO + IPI combo sustains response, OS benefit in aHCC

30 Aug 2022 by

The combination of nivolumab 1 mg/kg (NIVO1) and ipilimumab 3 mg/kg (IPI3) every 3 weeks followed by NIVO 240 mg every 2 weeks in the second-line setting continues to confer durable response and overall survival (OS) benefit in patients with advanced hepatocellular carcinoma (aHCC), according to 5-year data from the CheckMate 040* trial presented at ESMO GI 2022.

Second-line NIVO + IPI combo sustains response, OS benefit in aHCC

Latest glucose-lowering drug use and glycaemic outcome trends in HK

30 Aug 2022 by

A retrospective cross-sectional analysis of trends in glucose-lowering drug (GLD) use and glycaemic outcomes among Hong Kong’s 0.9 million adults with diabetes between 2002 and 2019 finds a levelling off in improvements since 2014.

Latest glucose-lowering drug use and glycaemic outcome trends in HK

30 Aug 2022

Early diagnosis and treatment of transthyretin amyloid cardiomyopathy significantly improves outcomes

30 Aug 2022 by

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a significantly underdiagnosed, life-threatening disease caused by the deposition of transthyretin amyloid fibrils in the heart. Dr Soon Chao Yang, Interventional Cardiologist at The Heart Doctors Clinic in Mount Alvernia Hospital, Singapore, reviews the data on early treatment of ATTR-CM, and shares his clinical experience with tafamidis.

Early diagnosis and treatment of transthyretin amyloid cardiomyopathy significantly improves outcomes

Revacept works in patients with internal carotid artery stenosis

Treatment with revacept 120 mg appears to be beneficial in the treatment of patients with symptomatic internal carotid artery stenosis, according to a study.

Revacept works in patients with internal carotid artery stenosis

RYGB in severe obesity leads to weight loss, hypertension remission

In patients with severe obesity, undergoing either laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (RYGB) resulted in weight loss, according to long-term follow-up of the SLEEVEPASS* trial. However, remission of hypertension was more likely in patients who underwent RYGB compared with LSG.

RYGB in severe obesity leads to weight loss, hypertension remission

29 Aug 2022

Combined oral contraceptives and VTE: Which pill conveys the highest risk in young women?

Combined oral contraceptives (COCs) that contain gestodene confer a fivefold increased risk of venous thromboembolism (VTE) in young women as compared with those that contain levonorgestrel and the lowest doses of ethinylestradiol, as shown in a study.

Combined oral contraceptives and VTE: Which pill conveys the highest risk in young women?

29 Aug 2022

1 in 10 adults experience sexual aversion, says study

Sexual aversion (SA), which is characterized by an unwillingness to get involved in any sexual activity, occurs in nearly 10 percent of adults, reveals a study in Canada.

1 in 10 adults experience sexual aversion, says study

Health-promoting behaviours mediate association between symptom severity and QoL in mental illness

Health-promoting behaviours mediate the association between psychiatric symptoms and quality of life (QoL) in people with mental health illnesses (PMI), researchers from the Chinese University of Hong Kong (CUHK) have reported.

Health-promoting behaviours mediate association between symptom severity and QoL in mental illness

Is malnutrition associated with poor outcomes after amputation?

The prevalence of malnutrition and its related outcomes in patients who underwent lower limb amputation (LLA) remain unclear due to the lack of research using validated nutrition assessment tools, but limited evidence showed a high prevalence of amputees at risk of malnutrition, according to a Singapore study.

Is malnutrition associated with poor outcomes after amputation?