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Meta-analysis: No link between PPI use and gastric cancer
Proton pump inhibitor (PPI) therapy does not appear to put individuals who require gastric acid suppression at increased risk of gastric cancer, according to a study.
Meta-analysis: No link between PPI use and gastric cancer
11 Jan 2023
Refractory Crohn’s disease responds well to risankizumab
In the treatment of patients with luminal Crohn’s disease and multiple prior drug failures, risankizumab induces clinical response in about three out of four patients and steroid-free clinical remission in about half, according to a study.
Refractory Crohn’s disease responds well to risankizumab
09 Jan 2023
Adagrasib shows antitumour activity in KRAS G12C-mutant colorectal cancer
Adagrasib appears to have some effect against metastatic, KRAS G12C-mutated colorectal cancer when used in treatment-experienced patients either as oral monotherapy or in combination with cetuximab, according to the results of a phase I-II, open-label study.
Adagrasib shows antitumour activity in KRAS G12C-mutant colorectal cancer
07 Jan 2023
Investigational antisense oligonucleotide for chronic HBV infection shows positive results
Treatment with the antisense oligonucleotide bepirovirsen appears to lead to sustained loss of hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA in up to 10 percent of patients with chronic HBV infection, according to the results of the phase IIb study B-Clear.
Investigational antisense oligonucleotide for chronic HBV infection shows positive results
06 Jan 2023
Procalcitonin-based algorithm reduces unnecessary antibiotic use in acute pancreatitis
A procalcitonin-guided algorithm could reduce the unnecessary use of antibiotics in patients with acute pancreatitis, according to results of the PROCAP trial.
Procalcitonin-based algorithm reduces unnecessary antibiotic use in acute pancreatitis
01 Jan 2023
Coeliac disease tied to higher risk of juvenile idiopathic, rheumatoid arthritis
Young patients with coeliac disease (CD) tend to develop juvenile idiopathic arthritis (JIA) three times more often than does the general population, while adult CD patients appear to have rheumatoid arthritis (RA) nearly twice as often, reveals a study.