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Surgery helps avoid castrate-resistant state in men with metastatic prostate cancer
In men with metastatic prostate cancer, prior radical prostatectomy (RP) appears to reduce the risk of developing a castrate-resistant state, as compared with radiation therapy (RT), according to a recent study. Previous RP also seems to improve overall survival (OS).
Surgery helps avoid castrate-resistant state in men with metastatic prostate cancer
05 Jul 2022Stage II CRC: ctDNA guidance reduces adjuvant chemo use, does not increase recurrence
Using circulating tumour DNA (ctDNA) analysis to guide adjuvant treatment of stage II colorectal cancer (CRC) reduces adjuvant chemotherapy use without compromising recurrence-free survival (RFS) compared with standard management guided by clinicopathological criteria, results of a phase II randomized controlled trial have shown.
Stage II CRC: ctDNA guidance reduces adjuvant chemo use, does not increase recurrence
05 Jul 2022Concurrent DOAC, tamoxifen use poses no elevated bleeding risk
In breast cancer patients receiving direct oral anticoagulants (DOACs), tamoxifen is safe to use and does not increase the risk of haemorrhage as compared with concurrent use of an aromatase inhibitor (AI), a study has found.
Concurrent DOAC, tamoxifen use poses no elevated bleeding risk
05 Jul 2022Deep submucosal invasion not independently linked to metastasis in colorectal cancer
In the absence of other histological risk factors, deep submucosal invasion is not strongly predictive of lymph node metastasis in patients with T1 colorectal cancer, reports a recent meta-analysis.