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Esaxerenone produces favourable night-time BP-lowering effect in Asians
The novel highly selective mineralocorticoid receptor blocker esaxerenone holds promise in the treatment of nocturnal hypertension, yielding substantial reductions in night-time blood pressure (BP), especially in Japanese patients with a riser pattern, as well as in N-terminal pro B-type natriuretic peptide (NT-proBNP) levels, according to a post hoc analysis of a phase III study.
Esaxerenone produces favourable night-time BP-lowering effect in Asians
24 Jan 2022
Peak exercise SBP below predicted value tied to future CVD, mortality
A peak systolic blood pressure (SBP) at clinical exercise testing that is slightly lower than the predicted value appears predictive of future cardiovascular disease (CVD) and mortality, suggests a study. Higher peak SBP, however, is not associated with such risks.
Peak exercise SBP below predicted value tied to future CVD, mortality
24 Jan 2022
KEEPsAKE findings boost risankizumab efficacy, safety for PsA
In individuals with psoriatic arthritis (PsA) who have inadequate response or intolerance to ≥1 csDMARD*, the monoclonal antibody risankizumab significantly improved manifestations of PsA, according to the 24-week findings of the phase III KEEPsAKE 1 trial.
KEEPsAKE findings boost risankizumab efficacy, safety for PsA
24 Jan 2022
PSA mRNA in circulating tumour cells a potential new biomarker for prostate cancer progression
Levels of prostate specific antigen (PSA) mRNA in circulating tumour cells can be used alongside serum PSA protein levels to refine the assessment of disease progression in patient with metastatic castration-resistant prostate cancer (mCRPC), a new study has found.
PSA mRNA in circulating tumour cells a potential new biomarker for prostate cancer progression
23 Jan 2022
Hypothyroidism not associated with worse prognosis in COVID-19
Patients with hypothyroidism who develop COVID-19 have a lower mechanical ventilation requirement and are less likely to die in the hospital, as reported in a study.
Hypothyroidism not associated with worse prognosis in COVID-19
23 Jan 2022
Depression rife in hidradenitis suppurativa
The prevalence of depression is relatively high among children, adolescents, and adults with hidradenitis suppurativa (HS), a chronic inflammatory skin disorder, according to a study, which also notes the importance of periodic screening for depression.