News & Updates

Most patients with inflammatory bowel disease (IBD) build an initial immune response to SARS-CoV-2 vaccination, but older patients, those treated with antitumour necrosis factor (anti-TNF) and an immunomodulator, and those on corticosteroids may require an additional vaccine dose to achieve better immunity against COVID-19, according to a study.

Implementation of an inpatient pancreatitis service appears to result in better outcomes in patients with mild acute pancreatitis, suggests a study. Guideline-based educational interventions deliver benefits on the management of this condition by admitting teams even without pancreatitis consultation.

The fibrosis-4 index (FIB-4) is strongly and independently associated with major adverse cardiovascular events (MACE), beyond established cardiovascular risk factors and baseline liver diagnosis, among patients with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), or at risk of NASH, a study in the real-world setting has shown.

Polypharmacy (PP) arises in nearly one in five patients with inflammatory bowel disease (IBD), particularly in older adults and those with comorbidity, according to a study, adding that PP can complicate adherence to treatment and therapeutic success.

Cases of severe alcohol-related hepatitis requiring inpatient management has dramatically increased during the COVID-19 pandemic, particularly in patients aged <40 years and in women, a study has found.