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ADT-docetaxel-abiraterone: A winning combo for mCSPC
Triplet therapy combining androgen deprivation therapy (ADT), docetaxel, and abiraterone-prednisone improves overall survival (OS) in men with de novo metastatic castration-sensitive prostate cancer (mCSPC), according to results of the phase III PEACE-1 trial presented at ESMO 2021.
ADT-docetaxel-abiraterone: A winning combo for mCSPC
07 Oct 2021In vitro fertilization may increase prevalence of erectile, male sexual dysfunction
The prevalence of erectile dysfunction is significantly higher among men participating in in vitro fertilization (IVF) in order to conceive compared to couples who conceived spontaneously, reveals a recent study. Such occurrence leads to a very high rate of phosphodiesterase-5 inhibitor use.
In vitro fertilization may increase prevalence of erectile, male sexual dysfunction
07 Oct 2021Systemic diseases, smoking history linked to more severe dry eye signs
Certain systemic diseases, such as Sjögren syndrome (SS), facial rosacea, rheumatoid arthritis (RA), and peripheral artery disease, and a history of daily cigarette smoking are significantly associated with more severe dry eye disease (DED) signs, a study has found.
Systemic diseases, smoking history linked to more severe dry eye signs
07 Oct 2021Acid suppression drugs counteract EGFR-TKIs for NSCLC treatment
Acid suppression (AS) medications, such as proton pump inhibitors (PPIs) and histamine type-2 receptor antagonists (H2RAs), weaken the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) in nonsmall cell lung cancer (NSCLC), resulting in worse survival outcomes, according to a recent Singapore meta-analysis.
Acid suppression drugs counteract EGFR-TKIs for NSCLC treatment
07 Oct 2021Novel drug helps lessen liver stiffness in high-risk NAFLD
Treatment with the novel, selective peroxisome proliferator-activated receptor α modulator (SPPARMα) pemafibrate appears to produce a significant reduction in liver stiffness but not in liver fat content in patients with high-risk nonalcoholic fatty liver disease (NAFLD), according to the results of a phase II trial.