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Alternative complement pathway upregulated in severe, critical COVID-19
In patients with severe coronavirus disease 2019 (COVID-19), the leptin and alternative complement pathways are hyperactivated, which in turn might lead to greater inflammation, a new study has found.
Alternative complement pathway upregulated in severe, critical COVID-19
01 Dec 2021Urinary proadrenomedullin predicts severity of community-acquired pneumonia in children
Urinary proadrenomedullin (proADM)/creatinine (Cr) ratio measured at the time of emergency department visit appears predictive of the development of severe outcomes in children with community-acquired pneumonia (CAP), with stronger discriminatory performance in radiographic disease, suggests a recent study.
Urinary proadrenomedullin predicts severity of community-acquired pneumonia in children
01 Dec 2021Child abuse increased during COVID-19 lockdown
Child abuse rates appear to have increased during the lockdowns imposed to control COVID-19 transmission, according to a study from the US presented at the 2021 American Academy of Pediatrics National Conference & Exhibition (AAP 2021).
Child abuse increased during COVID-19 lockdown
30 Nov 2021Childhood cancers often misdiagnosed as TB, leads to more deaths
Cancer is frequently misdiagnosed as tuberculosis (TB) in children due to the clinical and radiologic overlap of the two diseases, which then contributes to increased mortality in this population, reveals a recent study.
Childhood cancers often misdiagnosed as TB, leads to more deaths
30 Nov 2021Repurposing a broad-spectrum antiviral drug may help treat asymptomatic, mild COVID-19
The oral antiviral drug umifenovir, which is used to treat influenza, appears to be beneficial in COVID-19 patients who are asymptomatic or with mild symptoms, with a phase III study showing that the drug is well tolerated and can induce viral clearance within 5 days.
Repurposing a broad-spectrum antiviral drug may help treat asymptomatic, mild COVID-19
29 Nov 2021No causal link between COVID-19 and atrial fibrillation
Patients with the coronavirus disease 2019 (COVID-19), even those genetically predisposed to the disease, are not at increased risk of developing atrial fibrillation, and vice versa, a study has found.
No causal link between COVID-19 and atrial fibrillation
29 Nov 2021Convalescent plasma ineffective for COVID-19
A recent Singapore meta-analysis of randomized controlled trials (RCT) has found no clear clinical benefit to using convalescent plasma (CP) for patients with the coronavirus disease 2019 (COVID-19), especially in those with severe disease.