News &amp; Updates

Early albuminuria reduction with finerenone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) is responsible for a huge proportion of the treatment effect against CKD progression and facilitates a modest amount of the effect against cardiovascular outcomes, reports a study.

Albuminuria reduction accounts for treatment effect on CKD outcomes in T2D

17 Dec 2023

Remimazolam shows promise in procedural sedation

Procedural sedation with remimazolam delivers effective sedation without adversely affecting haemodynamics and respirations or lingering drowsiness, as reported in a study.

Remimazolam shows promise in procedural sedation

Long-term voxelotor use increases Hb, reduces haemolysis markers in patients with SCD

17 Dec 2023 by

Long-term treatment with voxelotor 1,500 mg led to sustained improvements in haemoglobin (Hb) levels and reductions in clinical markers of haemolysis among patients with sickle cell disease (SCD), according to an updated interim analysis of the HOPE open-label extension (OLE) study presented at ASH 2023.

Long-term voxelotor use increases Hb, reduces haemolysis markers in patients with SCD

$Supplementation does little to reduce fractures in schoolchildren with vitamin D deficiency$

Supplementation does little to reduce fractures in schoolchildren with vitamin D deficiency

Among schoolchildren with a high baseline prevalence of vitamin D deficiency, oral supplementation with vitamin D for 3 years is safe but falls short of reducing the risk of fracture, according to a study.

Supplementation does little to reduce fractures in schoolchildren with vitamin D deficiency

Weight loss with tirzepatide reversed after stopping treatment

16 Dec 2023 by

For individuals with overweight or obesity who are taking tirzepatide for weight management, continued treatment results in sustained and even augmented weight loss. When treatment is stopped, however, the achieved weight loss is substantially reversed.

Weight loss with tirzepatide reversed after stopping treatment

Hyperuricaemia tied to increased LV mass index in women

Hyperuricaemia is significantly associated with the presence of increased left ventricular (LV) mass index (LVMI) in women, but not in men, reveals a recent study.

Hyperuricaemia tied to increased LV mass index in women

Breakthrough SARS-CoV-2 infection does not affect blood sugar control in T1D patients

Patients with type 1 diabetes (T1D) who have been vaccinated against COVID-19 do not appear to have worsened glycaemic control, according to a study.

Breakthrough SARS-CoV-2 infection does not affect blood sugar control in T1D patients

Antiplatelet therapy de-escalation a promising strategy for East Asian patients undergoing PCI

De-escalation of antiplatelet therapy appears to yield more favourable outcomes compared with standard dual antiplatelet therapy (DAPT) in East Asian patients with acute coronary syndrome (ACS) who are undergoing percutaneous coronary intervention (PCI), as shown in a study.

Antiplatelet therapy de-escalation a promising strategy for East Asian patients undergoing PCI

Getting both COVID-19 and flu shots at once just as effective as separate vaccinations

15 Dec 2023 by

Coadministration of the BNT162b2 BA.4/5 bivalent mRNA COVID-19 vaccine (BNT162b2-biv) and the seasonal influenza vaccine (SIV) offers protection against the two infections, with an efficacy that is similar as when giving each vaccine alone, according to a study.

Getting both COVID-19 and flu shots at once just as effective as separate vaccinations

Frailty highly prevalent among older hypertensive adults