Product Highlight - Cresemba

Presentation:
Cap: Each capsule contains 100 mg isavuconazole (as 186.3 mg isavuconazonium sulfate).
Inj: Each vial contains 200 mg isavuconazole (as 372.6 mg isavuconazonium sulfate).

Indication: CRESEMBA is indicated in adults for the treatment of:
- invasive aspergillosis
- mucormycosis in patients for whom amphotericin B is inappropriate

Dosage & Administration: Cap: Loading dose: 2 cap (equiv to 200 mg) every 8 hr for first 48 hr (total administrations: 12 cap in 48 hrs). Maintenance dose: 2 cap (equiv to 200 mg) once daily, starting 12-24 hr after the last loading dose. CRESEMBA capsules can be taken with or without food. 
CRESEMBA capsules should be swallowed whole. Do not chew, crush, dissolve or open the capsules.

IV infusion: Loading dose: 1 vial every 8 hr for 1st 48 hr (total administrations: 6 vial in 48 hrs).
Maintenance dose: 1 vial once daily, starting 12-24 hr after the last loading dose.