Product Highlight - PROTHROMPLEX

Active ingredient: Human prothrombin complex

Indication: Treatment & perioperative prophylaxis of bleeding in acquired deficiency of prothrombin complex coagulation factors in adults eg, deficiency caused by treatment or overdose w/ vit K antagonists, when rapid correction of deficiency is required. Treatment & perioperative prophylaxis of haemorrhages in congenital deficiency of vit K-dependent coagulation factors in adults when purified specific coagulation factor concentrate is not available.

Dosage & Administration: IV Not to administer >2 mL/min (60 IU/min). Individualized dose. Max single dose: 50 IU/kg. Bleeding & perioperative prophylaxis of bleeding during vit K antagonist treatment INR >6 50 IU/kg, 4-6 35 IU/kg, 2-3.9 25 IU/kg.