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Intraoperative instability common in pheochromocytomas, paragangliomas despite good preparation
Pheochromocytomas (PCC) and paragangliomas (PGL) show a wide range of symptoms, with frequent intraoperative instability despite good preoperative preparation, according to a Singapore study. In addition, up to one-fifth of the patients in a single centre developed disease recurrences and metastasis.
Intraoperative instability common in pheochromocytomas, paragangliomas despite good preparation
11 Nov 2021
Dose-reduced ARPI leads to inferior survival in CRPC patients
Reduced-dose treatment with androgen receptor pathway inhibitors (ARPI) lead to poorer oncological outcomes relative to full-dose regimens in castration-resistant prostate cancer (CRPC), a recent study has found.
Dose-reduced ARPI leads to inferior survival in CRPC patients
09 Nov 2021
Hydrochlorothiazide use poses risk of cutaneous squamous cell carcinoma among diabetics
Type 2 diabetes (T2D) patients exposed to hydrochlorothiazide for more than 2 years appear to be at higher risk of cutaneous squamous cell carcinoma (cSCC), as reported in a recent study.
Hydrochlorothiazide use poses risk of cutaneous squamous cell carcinoma among diabetics
09 Nov 2021
Omeprazole helps inhibit fatty acid synthase activity in triple-negative breast cancer
Fatty acid synthase (FASN) is commonly expressed in operable triple-negative breast cancer (TNBC) and is associated with a poor prognosis, but omeprazole can hamper FASN activity, which may potentially boost the efficacy of neoadjuvant chemotherapy, according to the results of a phase II study.
