News & Updates

Scenario 1

03 Jul 2024 by

Treatment with linaclotide significantly improved abdominal symptoms and the frequency of complete spontaneous bowel movements (CSBMs) among adult and elderly patients with irritable bowel syndrome with constipation (IBS-C), according to the pooled analysis of three phase III trials presented at DDW 2024.

Scenario 1

03 Jul 2024

48-week data ASSERT odevixibat’s role in ALGS

29 May 2024 by

Pooled analysis of the ASSERT and ASSERT-EXT studies show sustained improvements in multiple parameters with odevixibat in individuals with Alagille syndrome (ALGS), thus reinforcing its role in the treatment of this multisystem genetic disorder.

48-week data ASSERT odevixibat’s role in ALGS

29 May 2024

Maralixibat may benefit certain subgroups of children with PFIC

28 May 2024 by

Maralixibat may have a role in treating a broader profile of children with PFIC, including those who have had biliary diversion surgery and those with MDR3 deficiency, suggest subgroup analyses from the phase III MARCH/MARCH-ON trials

Maralixibat may benefit certain subgroups of children with PFIC

28 May 2024

High-resolution anorectal manometry detects HD in children ≤2 years old

28 May 2024 by

High-resolution anorectal manometry (HR‐ARM) can be a noninvasive primary screening tool for Hirschsprung’s disease (HD), particularly in children ≤2 years old, as shown in a comprehensive retrospective analysis.

High-resolution anorectal manometry detects HD in children ≤2 years old

28 May 2024

Prednisone better than anakinra-zinc combo for severe alcohol-associated hepatitis

18 May 2024 by

Use of prednisone in patients with severe alcohol-associated hepatitis (SAH) results in significantly better overall and transplant-free survival at 90 days and a lower incidence of acute kidney injury (AKI) when compared with the use of anakinra plus zinc, results of a study have shown.

Prednisone better than anakinra-zinc combo for severe alcohol-associated hepatitis

18 May 2024

HCV cure possible in people who inject drugs despite poor treatment adherence

17 May 2024

People who inject drugs (PWID) with low adherence to sofosbuvir/velpatasvir can still be cured of hepatitis C virus (HCV) infection, suggests a study.

HCV cure possible in people who inject drugs despite poor treatment adherence

17 May 2024

Hepatic inflammation, fibrosis influence mid-term mortality in MASLD

07 May 2024

In patients with metabolic dysfunction-associated steatotic liver disease (MASLD), mid-term mortality increases in the presence of hepatic inflammation and fibrosis, as reported in a study.

Hepatic inflammation, fibrosis influence mid-term mortality in MASLD

07 May 2024

Gluten-free diet may improve liver, metabolic parameters in MASLD

28 Apr 2024

Following an amylase trypsin inhibitors (ATI)-free diet for 6 weeks appears to produce substantial improvements in liver and metabolic, as well as patient-reported outcomes, in people with metabolic dysfunction-associated steatotic liver disease (MASLD), according to a proof-of-concept study.

Gluten-free diet may improve liver, metabolic parameters in MASLD

28 Apr 2024

Third-line rescue therapy averts colectomy for some patients with acute severe ulcerative colitis

27 Apr 2024

Third-line rescue therapy appears to be a promising therapeutic strategy in acute severe ulcerative colitis, with a recent study showing that such an approach helps avoid colectomy in most patients.

Third-line rescue therapy averts colectomy for some patients with acute severe ulcerative colitis

27 Apr 2024

Supplementation with essential amino acid improves liver health in teen girls with PCOS

23 Apr 2024 by

Short-term supplementation with a selective essential amino acid (EAA)-containing product significantly improved liver-related outcomes among adolescent girls with polycystic ovarian syndrome (PCOS) in a recent study.

Supplementation with essential amino acid improves liver health in teen girls with PCOS

23 Apr 2024

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Scenario 1

Scenario 1

48-week data ASSERT odevixibat’s role in ALGS

48-week data ASSERT odevixibat’s role in ALGS

Maralixibat may benefit certain subgroups of children with PFIC

Maralixibat may benefit certain subgroups of children with PFIC

High-resolution anorectal manometry detects HD in children ≤2 years old

High-resolution anorectal manometry detects HD in children ≤2 years old

Prednisone better than anakinra-zinc combo for severe alcohol-associated hepatitis

Prednisone better than anakinra-zinc combo for severe alcohol-associated hepatitis

HCV cure possible in people who inject drugs despite poor treatment adherence

HCV cure possible in people who inject drugs despite poor treatment adherence

Hepatic inflammation, fibrosis influence mid-term mortality in MASLD

Hepatic inflammation, fibrosis influence mid-term mortality in MASLD

Gluten-free diet may improve liver, metabolic parameters in MASLD

Gluten-free diet may improve liver, metabolic parameters in MASLD

Third-line rescue therapy averts colectomy for some patients with acute severe ulcerative colitis

Third-line rescue therapy averts colectomy for some patients with acute severe ulcerative colitis

Supplementation with essential amino acid improves liver health in teen girls with PCOS

Supplementation with essential amino acid improves liver health in teen girls with PCOS