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Is first-line lazertinib monotherapy a potential new SoC for EGFRm NSCLC?
Patients with EGFR-mutated (EGFRm) advanced non-small cell lung cancer (NSCLC) exhibited significantly improved progression-free survival (PFS) when treated with lazertinib compared with gefitinib in the first-line setting, results of the LASER301 trial showed.
Is first-line lazertinib monotherapy a potential new SoC for EGFRm NSCLC?
10 Feb 2023Survival advantage in COVID-19 seen with 8-mg/kg tocilizumab
In the treatment of hospitalized patients with COVID-19, survival outcomes appear to be more favourable with the 8-mg/kg tocilizumab regimen than with the fixed-dose tocilizumab regimen or sarilumab, according to a study.
Survival advantage in COVID-19 seen with 8-mg/kg tocilizumab
09 Feb 2023Biologic agents raise IBD risk among axSpA patients
Based on observational studies, patients with axial spondyloarthritis (axSpA) treated with biologics are at higher risk of inflammatory bowel disease (IBD), while findings from randomized controlled trials (RCTs) suggest that treatment with etanercept (ETN) tends to increase such risk compared to other antitumour necrosis factor (anti-TNF) therapies, according to the result of a meta-analysis.
Biologic agents raise IBD risk among axSpA patients
08 Feb 2023Studies support vedolizumab benefit for IBD
Data presented at the Crohn’s & Colitis Congress (CCC) 2023 reflect the benefit of vedolizumab for inflammatory bowel disease (IBD; Crohn’s disease and ulcerative colitis), be it alone or in a combination regimen. In one study however, extraintestinal manifestations were observed following vedolizumab use.