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Neoadjuvant immunotherapy delivers in cisplatin-ineligible bladder cancer
The use of pembrolizumab in the neoadjuvant setting appears to be associated with a higher rate of downstaging and a survival advantage among patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based neoadjuvant chemotherapy, according to a study presented at this year’s ASCO Genitourinary Cancers Symposium.
Neoadjuvant immunotherapy delivers in cisplatin-ineligible bladder cancer
03 Mar 2023Nivolumab plus cabozantinib superior to sunitinib in renal cell carcinoma
First-line treatment of advanced renal cell carcinoma (aRCC) with nivolumab plus cabozantinib (N+C) results in sustained survival and response benefits at 3 years minimum follow-up, which is consistent with previous follow-ups, according to a study presented at the 2023 ASCO GU Cancers Symposium.
Nivolumab plus cabozantinib superior to sunitinib in renal cell carcinoma
03 Mar 2023FDRS variables predict Alzheimer's, dementia in HF, AF patients
Variables from the Framingham Heart Study Dementia Risk Score (FDRS) are predictive of Alzheimer’s disease (AD) and AD-related dementias (ADRD) in patients with heart failure (HF) or atrial fibrillation (AF), a study has shown.
FDRS variables predict Alzheimer's, dementia in HF, AF patients
03 Mar 2023How common is viral burden rebound in hospitalized COVID-19 patients with or without oral antiviral treatment?
A real-world study during Hong Kong’s Omicron BA.2.2 wave has shown that viral burden rebound is uncommon in hospitalized COVID-19 patients not requiring supplemental oxygen on admission, regardless of whether they were treated with nirmatrelvir/ritonavir or molnupiravir. However, immunocompromised patients, regardless of oral antiviral use, are more likely to have viral burden rebound.
How common is viral burden rebound in hospitalized COVID-19 patients with or without oral antiviral treatment?
03 Mar 2023Mirabegron, vibegron equally effective in postmenopausal women with OAB
Mirabegron appears to be as good as vibegron in the treatment of overactive bladder (OAB) in postmenopausal women, with both drugs helping improve symptoms and the parameters of voiding diary, according to a study.