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ALESIA: Long-term data support first-line alectinib in Asians with ALK-positive NSCLC
First-line treatment with alectinib appears to produce sustained clinical benefit in Asian patients with advanced, ALK-positive nonsmall cell lung cancer (NSCLC) through 5 years of follow-up, according to long-term data from the phase III ALESIA presented at the ESMO Asia Congress 2022.
ALESIA: Long-term data support first-line alectinib in Asians with ALK-positive NSCLC
09 Dec 2022Gut microbiome modulation reduces infections, shows other health benefits
A gut microbiota–derived synbiotic formula developed by researchers from the Chinese University of Hong Kong (CUHK) is shown in a randomized controlled trial to reduce the risk of bacterial and viral infections, including COVID-19, reduce the risk of adverse events (AEs) after COVID-19 vaccination, restore healthy gut microbiota, and provide other health benefits.
Gut microbiome modulation reduces infections, shows other health benefits
05 Dec 2022First-line serplulimab + chemo ups survival in extensive-stage SCLC
The addition of serplulimab to chemotherapy in the first-line setting improved overall survival (OS) in patients with extensive-stage small cell lung cancer (SCLC), according to results of the ASTRUM-005 trial.
First-line serplulimab + chemo ups survival in extensive-stage SCLC
02 Dec 2022Age, sex, syphilis risk factors for COVID-19 in PLHIV
Among people living with HIV (PLHIV), young women and patients with active syphilis appeared to be at an elevated risk of contracting COVID-19, according to a cross-sectional study presented at HIV Glasgow 2022.
Age, sex, syphilis risk factors for COVID-19 in PLHIV
30 Nov 2022Lung fibrosis extent on quantified CT predicts survival in IPF
The extent of fibrotic abnormality on baseline computed tomography (CT), quantified using data-driven texture analysis (DTA), is predictive of outcomes in patients with idiopathic pulmonary fibrosis (IPF), regardless of pulmonary function, suggests a study.
Lung fibrosis extent on quantified CT predicts survival in IPF
29 Nov 2022Vilobelimab augments treatment armamentarium for critically ill COVID-19 patients
In the phase III part of the PANAMO trial, the anti-C5a monoclonal antibody vilobelimab, when added to standard of care (SoC), improved survival in COVID-19 patients who required invasive mechanical ventilation (IMV).