News &amp; Updates

Chronic obstructive pulmonary disease (COPD) is associated with an earlier diagnosis of lung cancer, according to a cross-sectional, real-world study.

COPD tied to earlier lung cancer diagnosis

27 Jun 2022

Infliximab, adalimumab biosimilars effective, safe in paediatric IBD

The use of biosimilars of infliximab (IFX) and adalimumab (ADA) is both safe and effective in children with inflammatory bowel disease (IBD), inducing high rates of failure-free survival with a low incidence of adverse events, according to a study presented at the 2022 Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN 2022).

Infliximab, adalimumab biosimilars effective, safe in paediatric IBD

27 Jun 2022

Inability to stand on a leg for 10 sec tied to shorter life in older adults

Inability to stand on one leg for 10 seconds (sec) is strongly linked to a higher risk of death, and consequently, a shorter life expectancy in older adults, according to a study in Brazil.

Inability to stand on a leg for 10 sec tied to shorter life in older adults

Regular statin use offers protection against diabetes in acute pancreatitis patients

Regular statin users appear to be at lower risk of developing diabetes mellitus following an episode of acute pancreatitis, as shown in a study.

Regular statin use offers protection against diabetes in acute pancreatitis patients

Glargine, degludec improve glycaemic control in patients switching from first-gen insulin

Among type 2 diabetes (T2D) patients on first-generation basal insulins (1BIs), a switch to either glargine or degludec in the real-world setting leads to marked improvements in glucose control without increasing the risk of hypoglycaemic events and weight gain, according to a study. Furthermore, the benefits seem to be comparable between the two second-generation basal insulins (2BIs).

Glargine, degludec improve glycaemic control in patients switching from first-gen insulin

Antibody responses to COVID-19 vaccines in older people: Recent evidence & local data

Older adults have weaker antibody responses to two doses of COVID-19 vaccines [ie, mRNA-based BNT162b2 vaccine and inactivated CZ02 vaccine] vs younger individuals, but a booster dose mounts SARS-CoV-2 neutralization activities to a high level, according to data presented at AIM 2022.

Antibody responses to COVID-19 vaccines in older people: Recent evidence & local data

27 Jun 2022

Calorie restriction blunts long-term kidney decline, improves CV risk factors in obese T2D patients

In type 2 diabetes (T2D) patients with obesity, calorie restriction helps correct several cardiovascular (CV) risk factors and glomerular hyperfiltration, with the latter translating into a relative long-term stabilization of kidney function, according to a study.

Calorie restriction blunts long-term kidney decline, improves CV risk factors in obese T2D patients

Revacept beneficial to patients with symptomatic ICA stenosis

Patients with symptomatic internal carotid artery (ICA) stenosis may fare well with revacept, a competitive antagonist of glycoprotein VI, as the drug helps reduce the incidence of stroke or death, transient ischaemic attack, and bleeding complications, among others, according to a study.

Revacept beneficial to patients with symptomatic ICA stenosis

Specific carbohydrate diet may improve symptoms for some IBD patients

A specific carbohydrate diet (SCD) and a modified SCD (MSCD) demonstrate inconsistent effectiveness for the improvement of symptoms in inflammatory bowel disease (IBD), with some patients benefitting and others not, reports a study.

Specific carbohydrate diet may improve symptoms for some IBD patients

26 Jun 2022

$Add-on baclofen eases reflux in certain PPI-refractory GERD patients$

Add-on baclofen eases reflux in certain PPI-refractory GERD patients

In patients with proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease (GERD), add-on treatment with baclofen improves several reflux parameters, but only among those who are positive for symptom association probability, a study has found.

Add-on baclofen eases reflux in certain PPI-refractory GERD patients