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NAFLD linked to heightened type 2 diabetes risk
Children with nonalcoholic fatty liver disease (NAFLD) are at an increased risk of type 2 diabetes, a study reports. Other risk factors for T2D include severity of liver histology, body mass index, and female sex.
NAFLD linked to heightened type 2 diabetes risk
22 Jun 2022Acute kidney injury tied to poorer stroke survival, subsequent CKD development
The presence of acute kidney injury (AKI) during stroke appears to contribute to increased mortality, with AKI tending to progress to chronic kidney disease (CKD) even without the need for renal replacement therapy, a study has found.
Acute kidney injury tied to poorer stroke survival, subsequent CKD development
22 Jun 2022HBcrAg, HBsAb levels tied to persistent functional chronic hepatitis B cure
In chronic hepatitis B (CHB) patients treated with pegylated interferon alpha (peg-IFN-α)-based interventions, lower levels of the HB core-related antigen (HBcrAg) and higher levels of the HB surface antibody (HbsAb) are associated with durable functional cure, a recent study has found,
HBcrAg, HBsAb levels tied to persistent functional chronic hepatitis B cure
22 Jun 2022Lutein/zeaxanthin an appropriate substitute for beta carotene in AREDS2
Supplementation with lutein/zeaxanthin instead of beta carotene is safe and does not contribute to an increase in lung cancer risk while having a potential beneficial effect on the risk of progression to late age-related macular degeneration (AMD), according to data from the Age-Related Eye Disease Study 2 (AREDS2) study.
Lutein/zeaxanthin an appropriate substitute for beta carotene in AREDS2
21 Jun 2022Rapid childhood growth rate tied to elevated risk of islet autoimmunity, T1D development
Children who grow in height fast appears to have a higher risk of islet autoimmunity (IAA) and rapid progression to type 1 diabetes (T1D), a study has found.
Rapid childhood growth rate tied to elevated risk of islet autoimmunity, T1D development
21 Jun 2022Normal weight obesity in adolescents tied to cardiometabolic risk
Adolescents with normal weight obesity (NMO) may present with several cardiometabolic risk factors, putting them at greater risk of developing vascular events or diabetes, suggests a recent study.
Normal weight obesity in adolescents tied to cardiometabolic risk
21 Jun 2022How effective were oral antivirals during HK’s Omicron BA.2 wave?
A real-world study during Hong Kong’s Omicron BA.2 wave showed that both molnupiravir and nirmatrelvir/ritonavir effectively lowered the risks of disease progression and all-cause mortality in hospitalized COVID-19 patients not requiring oxygen supplementation on admission. However, mortality risk reduction was larger with nirmatrelvir/ritonavir vs molnupiravir.
How effective were oral antivirals during HK’s Omicron BA.2 wave?
21 Jun 2022Nintedanib falls short in bladder cancer trial
In the phase II NEOBLADE* trial, the addition of the multikinase** inhibitor nintedanib to neoadjuvant chemotherapy (CT) consisting of gemcitabine and cisplatin failed to improve pathological complete response (pCR) and progression-free survival (PFS) in individuals with locally advanced muscle-invasive bladder cancer (MIBC).