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![DPP-4–to–SGLT2 inhibitor switch confers multiple benefits for patients with diabetes, hypertension](https://sitmspst.blob.core.windows.net/images/articles/certain-cv-risk-reductions-with-sglt2-inhibitors-limited-to-patients-with-atherosclerotic-cvd-b88808b9-f63d-4818-8723-8a0a2c93197e-square.jpg)
DPP-4–to–SGLT2 inhibitor switch confers multiple benefits for patients with diabetes, hypertension
In the treatment of patients with type 2 diabetes mellitus and hypertension, switching from a dipeptidyl peptidase-4 (DPP-4) inhibitor to the sodium-glucose cotransporter-2 (SGLT2) inhibitor luseogliflozin appears to have favourable effects on blood pressure (BP), circadian rhythm, and night-time systolic BP (SBP) and pulse rate (PR), according to data from the open-label LUNA trial.
DPP-4–to–SGLT2 inhibitor switch confers multiple benefits for patients with diabetes, hypertension
28 Sep 2021![NSAIDs: suitable prophylaxis after cataract surgery?](https://sitmspst.blob.core.windows.net/images/articles/prednisolone-ketorolac-81c25f85-c0d3-426f-a498-62f0b45134f4-square.jpg)
NSAIDs: suitable prophylaxis after cataract surgery?
The addition of corticosteroids (ie, prednisolone) to NSAID eyedrops (ie, ketorolac) did not provide additional benefit relative to ketorolac alone or dropless surgery using a sub-Tenon capsule depot as an anti-inflammatory prophylactic regimen to prevent postoperative central macular thickening following uncomplicated cataract surgery, a Danish study suggests.
NSAIDs: suitable prophylaxis after cataract surgery?
28 Sep 2021![Side effects limit long-term therapy for primary aldosteronism](https://sitmspst.blob.core.windows.net/images/articles/paediatric-adrenal-insufficiency-t1d-may-impact-covid-19-outcomes-db59aa91-f8cb-4d64-a58b-b71baf8aad6e-square.jpg)
Side effects limit long-term therapy for primary aldosteronism
Long-term medical therapy in patients with primary aldosteronism (PA) is held back by dose-dependent side effects, according to a recent Singapore study.
Side effects limit long-term therapy for primary aldosteronism
28 Sep 2021![COMS IRIS plaque radiotherapy safe, effective against melanoma](https://sitmspst.blob.core.windows.net/images/articles/adjuvant-sunitinib-confers-overall-survival-advantage-in-uveal-melanoma-fa61e7d2-85b8-4bbf-b127-fe1984002e3f-square.jpg)
COMS IRIS plaque radiotherapy safe, effective against melanoma
The use of Collaborative Ocular Melanoma Study (COMS) IRIS plaques is an effective treatment approach to iris, iridociliary, and ciliary body melanoma, a recent study has found.
COMS IRIS plaque radiotherapy safe, effective against melanoma
28 Sep 2021![High-flowrate air samplers allow thorough monitoring for airborne SARS-CoV-2](https://sitmspst.blob.core.windows.net/images/articles/covid-19-airborne-threat-possible-especially-indoor-5aabb941-8c1e-42c6-a27e-3bc1ea4c2ec8-square.jpg)
High-flowrate air samplers allow thorough monitoring for airborne SARS-CoV-2
High-flowrate air samplers are able to detect airborne SARS-CoV-2 in hospitals, outperforming even surface sampling, according to a recent Singapore study. Factors such as the site of deployment and distance of the air samplers from patients affect the viral load detected.