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Cetuximab plus chemoradiotherapy feasible in women with cervical carcinoma
Treatment with cetuximab plus cisplatin 30 mg/m2 and radiotherapy appears safe and well tolerated in women with cervical carcinoma, a study has shown. In addition, fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) has exhibited early evidence of response to neoadjuvant cetuximab.
Cetuximab plus chemoradiotherapy feasible in women with cervical carcinoma
16 Jul 2022Upfront ASCT + RVd improves PFS in NDMM
Upfront autologous stem cell transplantation (ASCT) plus lenalidomide, bortezomib, and dexamethasone (RVd) significantly improves progression-free survival (PFS) in patients with newly diagnosed multiple myeloma (NDMM), results of the phase III DETERMINATION trial showed.
Upfront ASCT + RVd improves PFS in NDMM
16 Jul 2022Family history plus obesity/hyperglycaemia redoubles renal cell cancer risk
The interaction between genetic and environmental factors, specifically obesity and hyperglycaemia, contributes to an increased risk of renal cell cancer (RCC), suggests a study.
Family history plus obesity/hyperglycaemia redoubles renal cell cancer risk
16 Jul 2022Nonoperative management safe, feasible after complete response in rectal cancer
Patients with locally advanced rectal cancer who achieve complete response (CR) following sequential short-course radiation therapy (SCRT) and chemotherapy appear to benefit from nonoperative management (NOM) with a watch-and-wait strategy, which presents evidence for good anorectal functions, results of a study have shown.
Nonoperative management safe, feasible after complete response in rectal cancer
15 Jul 2022Olaparib safe, effective in ovarian cancer patients with BRCA mutation, HRD
Olaparib demonstrates clinical activity across patients with platinum-sensitive relapsed ovarian cancer and known BRCA mutation and homologous recombination deficiency (HRD), as shown in the phase II LIGHT study.
Olaparib safe, effective in ovarian cancer patients with BRCA mutation, HRD
15 Jul 2022Trastuzumab deruxtecan for HER2-low breast cancer: A treatment for a new population
Trastuzumab deruxtecan led to greater survival outcomes than chemotherapy treatment of physician’s choice (TPC)* in patients with HER2-low** advanced breast cancer, according to results of a phase III trial presented at ASCO 2022.
Trastuzumab deruxtecan for HER2-low breast cancer: A treatment for a new population
14 Jul 2022PSA testing helps prevent prostate cancer deaths
A prostate specific antigen (PSA)-based screening is effective in significantly lowering the risk of death from prostate cancer (PC), reports a study. However, nonattendance, initiation after age 60 years, and discontinuation at age 70 years appear to increase such risk.