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Pharmacists have seen improvements in safety outcomes following the change to vancomycin area under the curve (AUC) therapeutic drug monitoring, according to a study. Efficacy, on the other hand, appears similar if not increased.
Ethnicity seems to play a strong role in diabetes-related lower extremity complications (DRLEC), according to a recent Singapore study. Malays, in particular, are most likely to progress to DRLEC and require an amputation.
In patients with symptomatic knee osteoarthritis, treatment with atorvastatin falls short of reducing cartilage volume loss over 2 years as compared with placebo, according to the results of a trial.
In nursing homes, vaccinating against the novel coronavirus disease (COVID-19) seems to rapidly reduce the rates of infection, morbidity, and mortality, a recent study has found.
Women exposed to menopausal hormone therapy, including oestrogen‐only preparations and oestrogen combined progestin therapy, appear to have a lower risk of colorectal adenocarcinoma, a study has found.
Individuals with a history of schizophrenia spectrum disorder may have an elevated risk of COVID-19–related mortality, according to a retrospective cohort study from the US. However, the increased mortality risk did not apply to patients with anxiety or mood disorders.
In patients with acute decompensated heart failure (ADHF), the use of anxiolytic benzodiazepines may worsen the risk of severe delirium, a recent study has found.
Patients with active luminal Crohn’s disease are likely to achieve radiologic response and remission with infliximab trough level of 7.8 µg/ml at the end of induction therapy, as indicated by data from the TAILORIX trial.
Glucose control among postoperative cardiac surgery patients with prediabetes or diabetes receiving dipeptidyl peptidase-4 inhibitors (DPP-4i) plus basal insulin is similar to those on other regimens, a study has shown. In addition, use of DPP-4i does not result in hypoglycaemia.
Ascitic drain removal (ADR) within 24 hours among cirrhosis patients with refractory ascites appears to lower the risk of ascitic drain-related bacterial peritonitis (AdBP) and acute kidney injury (AKI), according to a Singapore study.
