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SMAD7 overexpression boosts EGFR-CAR-T function against NSCLC
Epidermal growth factor receptor (EGFR)-mothers against decapentaplegic homologue 7 (SMAD7)-Chimeric antigen receptor (CAR) T-cell therapy against nonsmall-cell lung cancer (NSCLC) is on a par with EGFR-dominant‒negative transforming growth factor (TGFbeta) receptor 2 (DNR)-CAR-T in terms of efficacy and resistance to negative TGFβ regulation, a study has shown.
SMAD7 overexpression boosts EGFR-CAR-T function against NSCLC
10 Sep 2023
Airflow limitation predicts muscle wasting in COPD patients
Severe airflow limitation tends to contribute to future muscle wasting in patients with chronic obstructive pulmonary disease (COPD) and ever-smokers at risk of COPD, reports a recent study.
Airflow limitation predicts muscle wasting in COPD patients
09 Sep 2023
Primary PCI strategy reduces death rates in STEMI patients
Between 2003 and 2018, 1-year mortality has decreased considerably in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) in a high-income European country with a fully implemented primary PCI strategy, reports a study.
Primary PCI strategy reduces death rates in STEMI patients
09 Sep 2023
Inadequate sleep tied to higher incidence of urgent urinary incontinence
Urgent urinary incontinence appears to occur more frequently among people with insufficient sleep than among those with moderate sleep duration, according to a study.