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Treatment with brolucizumab results in a longer interval between injections of antivascular endothelial growth factor (anti-VEGF) agents for most treatment-experienced eyes, especially those with shorter intervals before switching, while maintaining or improving visual acuity (VA), reports a study.

Brolucizumab prolongs interval of anti-VEGF injections in nAMD patients

Dexamethasone superior to ranibizumab, methotrexate for recurrent uveitic ME

Treatment with dexamethasone implant results in better outcomes for patients with persistent or recurrent uveitic macular edema (ME) at 12 weeks when compared with methotrexate or ranibizumab, a study has shown. The risk of intraocular pressure (IOP), however, is higher with dexamethasone, but elevations to levels of 30 mm Hg or more are rare.

Dexamethasone superior to ranibizumab, methotrexate for recurrent uveitic ME

The Geneva patient: Another score on the HIV remission board

Another HIV patient may be on the way to a cure following stem cell therapy using wild-type (WT) CCR5 donor cells for a rare and aggressive blood cancer.

The Geneva patient: Another score on the HIV remission board

Ribociclib có thể có vai trò trong điều trị ung thư vú giai đoạn sớm

Trong phân tích tạm thời thứ hai về hiệu quả của thử nghiệm pha III NATALEE, phác đồ kết hợp bao gồm thuốc ức chế CDK4/6 ribociclib và liệu pháp nội tiết (ET) đã cho thấy các dấu hiệu tich trong điều trị hỗ trợ đối với bệnh nhân ung thư vú giai đoạn sớm II/III có thụ thể nội tiết dương tính, HER2 âm tính (HR+, HER2–).

Ribociclib có thể có vai trò trong điều trị ung thư vú giai đoạn sớm

Healthy lifestyle, high Life's Essential 8 score protective in people with type 2 diabetes

For individuals with type 2 diabetes, leading a healthy lifestyle and scoring high on the American Heart Association (AHA)’s Life's Essential 8 (LE8) metric can lead to lower risks of developing macrovascular and microvascular diseases, as shown in a study.

Healthy lifestyle, high Life's Essential 8 score protective in people with type 2 diabetes

Meta-analysis: TTFields added to SoC improves OS in newly diagnosed GBM in real-world setting

Results of a systematic review and meta-analysis suggest that adding tumour-treating fields (TTFields) to standard chemoradiotherapy (CRT) significantly prolongs overall survival (OS) for patients with newly diagnosed glioblastoma multiforme (GBM) treated in the real-world setting.

Meta-analysis: TTFields added to SoC improves OS in newly diagnosed GBM in real-world setting

Original New Drug Application Approvals by US FDA (16-31 August 2023)

New drug applications approved by US FDA as of 16-31 August 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 August 2023)

Antibiotic use, resistance rates low after a decade of stewardship efforts in SG

31 Aug 2023 bởi

Ten years since the implementation of antimicrobial stewardship programmes (ASP) in Singapore, the use of several types of antibiotics has dropped, followed by reductions in antimicrobial resistance across several classes, as reported in a study.

Antibiotic use, resistance rates low after a decade of stewardship efforts in SG

What is the leading cause of blindness in children?

Retinopathy of prematurity (ROP) appears to be the leading cause of childhood blindness, reveals a recent study in the US. More than half of these blind patients have had a treatable cause of blindness.

What is the leading cause of blindness in children?

Complications risk low among hospitalized patients with spin-induced exertional rhabdomyolysis

31 Aug 2023 bởi

Management of hospitalized individuals with spin-induced exertional rhabdomyolysis (SER) includes hydration, oral analgesia, and basic laboratory investigations, according to a Singapore study, noting that the risk of complications in these patients is low.

Complications risk low among hospitalized patients with spin-induced exertional rhabdomyolysis