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FTD/TPI-bevacizumab combo a new SoC for metastatic CRC?
A combination of trifluridine/tipiracil (FTD/TPI) and bevacizumab provided significant survival benefit when used as third-line treatment for refractory metastatic colorectal cancer (CRC) than FTD/TPI alone, findings from the phase III SUNLIGHT study suggest.
FTD/TPI-bevacizumab combo a new SoC for metastatic CRC?
16 Feb 2023Dynapenia ups risks of falls, fractures in women with obesity
Reduced muscle strength (dynapenia) is associated with a higher risk of leg and ankle fractures in women with obesity, as shown in a study. Dynapenia also negates the protective effects of obesity on fractures of the wrist, arm, hip, spine, and other bones, thus increasing the risk of falls.
Dynapenia ups risks of falls, fractures in women with obesity
16 Feb 2023Prophylactic aflibercept reduces vision-threatening complications without gains in visual acuity
Treatment with intravitreal aflibercept in patients with nonproliferative diabetic retinopathy but without centre-involved diabetic macular edema appears to slow disease progression and reduce the risk of developing vision-threatening complications but fall short of improving visual acuity, according to a study.
Prophylactic aflibercept reduces vision-threatening complications without gains in visual acuity
15 Feb 2023Outpatient oritavancin bests inpatient SoC in acute uncomplicated cellulitis
Outpatient oritavancin therapy appears to be more effective than inpatient standard-of-care (SoC) in reducing 30-day hospital readmissions or admissions among individuals with acute uncomplicated cellulitis, a recent study has shown.
Outpatient oritavancin bests inpatient SoC in acute uncomplicated cellulitis
15 Feb 2023High-intensity exercise improves BP, body composition of hypertensive patients
The inclusion of a moderate- (MT) or high-intensity training (HIT) program as adjuvant therapy in hypertensive patients appears beneficial in reducing certain cardiovascular risks, but only HIT is effective at lowering blood pressure (BP) and losing body mass and fat, reports a study.