Metabolic Dysfunction-Associated Steatotic Liver Disease Disease Summary

Overview

Metabolic dysfunction-associated steatotic liver disease is considered as a hepatic manifestation of metabolic syndrome (obesity, type 2 diabetes mellitus, insulin resistance, dyslipidemia
and hypertension). 

It is associated with increased risk of cardiovascular disease which is due to increased oxidative stress, systemic or hepatic insulin resistance, low-grade inflammation and endothelial dysfunction.

It can progress to liver fibrosis and progressive liver disease over time including cirrhosis and hepatocellular carcinoma.