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Clinical Presentation
Respiratory
symptoms of pneumonia include an acute cough, which can either be nonproductive
or productive of purulent or rust-colored sputum, and at least one abnormal chest
finding (eg diminished breath sounds, rhonchi, crackles, or wheeze). Systemic
symptoms may also occur which include pleuritic chest pain, chills or rigors, and
confusion. Abnormal vital signs that prompt suspicion include a respiratory
rate of >20 breaths/minute, heart rate of >100 beats/minute, and fever
>37.8°C. Chest X-ray findings may show lobar consolidation, bilateral
infiltrates, or cavitation. It is potentially life-threatening, especially in older
adults and those with comorbid disease.
Low-risk Community-acquired Pneumonia (CAP)
Patients classified under low-risk community-acquired pneumonia do not have any alteration in mental status, have no suspicion of possible aspiration, do not have any comorbid condition, or have stable comorbid condition(s). Chest X-ray findings may show localized infiltrates but without pleural effusion.
They also typically present with the following vital signs:
- Respiratory rate of <30 breaths/minute
- Heart rate of <125 beats/minute
- Temperature of >36°C or <40°C
- Systolic blood pressure of >90 mmHg
- Diastolic blood pressure >60 mmHg
Moderate-risk
Community-acquired Pneumonia (CAP)
Patients classified under moderate-risk
community-acquired pneumonia may have an acute onset of altered mental state,
suspected aspiration, extrapulmonary evidence of sepsis (eg endocarditis,
arthritis, encephalitis, otitis media), or an unstable comorbid condition (eg uncontrolled
diabetes mellitus, active malignancies, congestive heart failure class II-IV, chronic
obstructive pulmonary disease in acute exacerbation, decompensated liver
disease). Chest X-ray findings may show bilateral or multilobar involvement, progression
of the lesion to 50% of initial finding within 24 hours, pleural effusion, or
abscess.
They also typically
present with the following vital signs:
- Respiratory rate of ≥30 breaths/minute
- Heart rate of ≥125 beats/minute
- Temperature of ≤36°C or ≥40°C
- Systolic blood pressure of <90 mmHg
- Diastolic blood pressure of ≤60 mmHg
High-risk
Community-acquired Pneumonia (CAP)
Clinical
Features
Patients classified under high-risk
community-acquired pneumonia exhibit either one major criterion or ≥3 minor
criteria.
The minor criteria are as follows:
- Respiratory rate of ≥30 breaths/minute
- Arterial oxygen partial pressure/Fractional inspired oxygen (PaO2/FiO2) ratio of ≤250 mmHg
- Multilobar infiltrates
- Confusion or disorientation
- Blood urea nitrogen (BUN) of ≥20 mg/dL
- White blood cell count (WBC) <4000 cells/μL
- Platelet count <100,000/μL
- Core temperature <36°C
- Hypotension needing aggressive fluid resuscitation
The major criteria are as follows:
- Septic shock needing vasopressors
- Respiratory failure needing mechanical ventilation
Diagnosis or Diagnostic Criteria
All
patients suspected of community-acquired pneumonia should have a chest
radiograph to establish the diagnosis and identify complications (eg pleural
effusion, multilobar disease). The definite diagnosis of community-acquired
pneumonia must be based on a combination of clinical features and a chest
radiograph showing lung shadowing that is likely to be new and not due to other
causes. Combining history and physical examination findings may be used to
presumptively identify patients with pneumonia in cases where a chest X-ray
might not be easy to perform.
Site-of-Care Decision
Clinical
judgment with a validated clinical prediction rule should be used to determine
the best site of care for patients. Other factors to be considered aside from
clinical severity include the ability of the patient to maintain oral intake,
cognitive or functional impairment, the likelihood of medication adherence,
history of substance abuse, severe comorbid illness, mental illness, and living
or social circumstances.