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Atezolizumab-bevacizumab combo trumps sorafenib for advanced HCC
The combination of atezolizumab and bevacizumab is better than sorafenib at maintaining clinically meaningful survival benefits over the long term in patients with unresectable hepatocellular carcinoma (HCC), reports a recent update to the IMbrave150 study.
Atezolizumab-bevacizumab combo trumps sorafenib for advanced HCC
27 Mar 2022Polymeric immunoglobulin receptor boosts cancer stemness, tumorigenesis in HCC patients
Extracellular vesicles enriched with the polymeric immunoglobulin receptor molecule contributes to tumorigenesis and cancer stemness in patients with hepatocellular carcinoma (HCC), reports a recent study.
Polymeric immunoglobulin receptor boosts cancer stemness, tumorigenesis in HCC patients
26 Mar 2022Respiratory-gated PET-CT improves liver tumour imaging
A prospective clinical study conducted by the Hong Kong Baptist Hospital in collaboration with the Hong Kong Polytechnic University has demonstrated the feasibility of implementing respiratory-gated PET-CT for liver malignancies with improved image quality compared with ungated scans.
Respiratory-gated PET-CT improves liver tumour imaging
17 Mar 2022Immune-related adverse events portend better prognosis in ICI-treated hepatocellular carcinoma
Among advanced hepatocellular carcinoma patients being treated with immune checkpoint inhibitors (ICIs), the occurrence of multisystem and more severe immune-related adverse events is a favourable signal, being associated with survival advantage, according to a Singapore study.
Immune-related adverse events portend better prognosis in ICI-treated hepatocellular carcinoma
08 Mar 2022Universal HCV screening in pregnancy: A step toward reducing transmission?
Universal screening for hepatitis C virus (HCV) in pregnant individuals resulted in improved detection and a potential reduction in perinatal transmission, according to a study presented at CROI 2022.
Universal HCV screening in pregnancy: A step toward reducing transmission?
01 Mar 2022KEYNOTE-394 a win for Asians with advanced HCC
Combining pembrolizumab with best supportive care (BSC) improved survival and response when used as second-line therapy in Asians with advanced hepatocellular carcinoma (HCC).
KEYNOTE-394 a win for Asians with advanced HCC
01 Mar 2022Hepatitis C reinfection rates up in direct-acting antiviral era
There is an increased rate of hepatitis C virus (HCV) reinfection among people who inject drugs after the scale-up of direct-acting antivirals, reports a recent Scotland study.
Hepatitis C reinfection rates up in direct-acting antiviral era
26 Feb 2022STRIDE regimen boosts OS in unresectable HCC
The addition of tremelimumab to durvalumab (STRIDE regimen) in the first-line setting improved overall survival (OS) compared with sorafenib in patients with advanced unresectable hepatocellular carcinoma (HCC), according to results of the phase III HIMALAYA trial.