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Laboratory Tests and Ancillaries
Diagnostic
tests may be necessary for complicated or atypical diseases. There are no
serologic markers or pathognomonic laboratory tests for psoriasis. Skin biopsy,
serologic studies for syphilis, bacterial culture, human leukocyte antigen
(HLA) typing, and microscopic (potassium hydroxide) examinations may be used to
differentiate psoriasis from other conditions.
Baseline studies should
include a complete blood count (CBC) with platelet, creatinine, electrolytes, liver
function tests, hepatitis panel screening, latent tuberculosis (TB) screening, and
human immunodeficiency virus (HIV) screening. It should be advised prior to
starting, resuming, or increasing therapy with systemic and immunosuppressive
agents.